Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GART | P22102 | 18/20 | 0.66 |
| ▸ | ATIC | P31939 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | FOLR2 | P14207 | 1/20 | 0.41 |
| ▸ | FOLR1 | P15328 | 1/20 | 0.41 |
| ▸ | SLC46A1 | Q96NT5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9794872 | 0.85 | GART (0.58) | GARTATICMAPT | |
| SCHEMBL9038667 | 0.83 | GART (0.64) | GARTATIC | |
| SCHEMBL9794867 | 0.82 | GART (0.66) | GARTATICMAPT | |
| SCHEMBL7608106 | 0.81 | GART (0.50) | GARTKDM4EMAPTFOLR2FOLR1 | |
| SCHEMBL9794844 | 0.80 | GART (1.00) | GARTATICFOLR2FOLR1SLC46A1 | |
| SCHEMBL7609762 | 0.79 | GART (0.66) | GARTATICFOLR1 | |
| SCHEMBL8342572 | 0.76 | GART (0.44) | GARTATICKDM4EMAPT | |
| SCHEMBL9794858 | 0.75 | GART (0.72) | GARTATICFOLR2FOLR1SLC46A1 | |
| SCHEMBL9794852 | 0.75 | GART (0.72) | GARTATICFOLR2FOLR1SLC46A1 | |
| SCHEMBL24809445 | 0.74 | GART (0.69) | GARTFOLR2FOLR1SLC46A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409382-A1 | Glutamic acid derivatives | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-01-23 | — | — | EP | disclosed |
| WO-1990014340-A1 | GLUTAMIC ACID DERIVATIVES | THE WELLCOME FOUNDATION LIMITED (GB) | 1990-11-29 | — | — | WO | disclosed |
| US-4921836-A | ANTITUMOR AGENTS | BURROUGHS WELLCOME CO. (US) | 1990-05-01 | — | — | US | disclosed |