Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9019581 | 0.84 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1SMN1; SMN2BCHELMNA | |
| SCHEMBL9497713 | 0.81 | BCHE (0.35) | ALDH1A1BCHE | |
| SCHEMBL9498023 | 0.81 | BCHE (0.35) | ALDH1A1BCHE | |
| SCHEMBL9795372 | 0.81 | HSD11B1 (0.37) | HSD11B1ALDH1A1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL9795054 | 0.81 | TDP1 (0.36) | ALDH1A1BCHE | |
| SCHEMBL9795195 | 0.81 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1SMN1; SMN2BCHELMNA | |
| SCHEMBL9130345 | 0.79 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1SMN1; SMN2BCHELMNA | |
| SCHEMBL9497857 | 0.78 | SMYD3 (0.44) | ALDH1A1L3MBTL1SMYD3 | |
| SCHEMBL9497980 | 0.78 | SMYD3 (0.44) | ALDH1A1L3MBTL1SMYD3 | |
| SCHEMBL9795527 | 0.78 | SMYD3 (0.44) | ALDH1A1L3MBTL1SMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037849-A | For treatment of heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |