Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 9/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9795608 | 0.83 | ALOX5 (0.40) | ALOX5L3MBTL1MAPTHSD17B10HSP90AA1 | |
| SCHEMBL9795595 | 0.83 | ALOX5 (0.59) | ALOX5MAPTMGLLADRB1 | |
| SCHEMBL9795597 | 0.82 | ALOX5 (0.58) | ALOX5MAPTHSD17B10MGLLADRB1 | |
| SCHEMBL9795564 | 0.81 | ALOX5 (0.56) | ALOX5L3MBTL1MAPTMGLLOPRM1 | |
| SCHEMBL9795531 | 0.81 | ALOX5 (0.57) | ALOX5L3MBTL1MGLL | |
| SCHEMBL9795631 | 0.81 | FAAH (0.44) | ALOX5MGLL | |
| SCHEMBL9795591 | 0.81 | ALOX5 (0.59) | ALOX5MGLL | |
| SCHEMBL9795775 | 0.81 | ALOX5 (0.40) | ALOX5MAPT | |
| SCHEMBL9795754 | 0.80 | ALOX5 (0.54) | ALOX5MAPTMGLLADRB1 | |
| SCHEMBL9795652 | 0.79 | ADRB1 (0.40) | ALOX5MAPTHSD17B10ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023255-A | Triazine derivatives; inhibitors exzyme 5-lipoxygenase | GLAXO GROUP LIMITED (GB) | 1991-06-11 | — | — | US | claimed |
| EP-0388165-A2 | Chemical compounds | GLAXO GROUP LIMITED (GB) | 1990-09-19 | — | — | EP | claimed |
| US-5023255-A | Triazine derivatives; inhibitors exzyme 5-lipoxygenase | GLAXO GROUP LIMITED (GB) | 1991-06-11 | — | — | US | disclosed |
| EP-0388165-A2 | Chemical compounds | GLAXO GROUP LIMITED (GB) | 1990-09-19 | — | — | EP | disclosed |