Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9795641 | 0.83 | ALOX5 (0.60) | ALOX5MAPTHSD17B10L3MBTL1HSP90AA1 | |
| SCHEMBL9795754 | 0.82 | ALOX5 (0.54) | ALOX5MAPTLMNAPKM | |
| SCHEMBL9795544 | 0.79 | ALOX5 (0.56) | ALOX5MAPTALDH1A1 | |
| SCHEMBL9795652 | 0.78 | ADRB1 (0.40) | ALOX5MAPTHSD17B10NPSR1ALDH1A1 | |
| SCHEMBL9795750 | 0.74 | ALOX5 (0.35) | ALOX5MAPTPKM | |
| SCHEMBL9795683 | 0.72 | CMA1 (0.36) | ALOX5MAPTL3MBTL1ALDH1A1LMNA | |
| SCHEMBL9644582 | 0.71 | ALOX5 (0.71) | ALOX5 | |
| SCHEMBL9795576 | 0.71 | ALOX5 (0.54) | ALOX5ALDH1A1LMNA | |
| SCHEMBL9795690 | 0.71 | ALOX5 (0.40) | ALOX5MAPTALDH1A1PKM | |
| SCHEMBL9795578 | 0.71 | MMP13 (0.40) | ALOX5HSD17B10NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023255-A | Triazine derivatives; inhibitors exzyme 5-lipoxygenase | GLAXO GROUP LIMITED (GB) | 1991-06-11 | — | — | US | disclosed |
| EP-0388165-A2 | Chemical compounds | GLAXO GROUP LIMITED (GB) | 1990-09-19 | — | — | EP | disclosed |