Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CTSG | P08311 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.37 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.37 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9795750 | 0.86 | ALOX5 (0.35) | MAPTALOX5 | |
| SCHEMBL9795683 | 0.84 | CMA1 (0.36) | KMT2AMEN1ALDH1A1MAPTCMA1 | |
| SCHEMBL9795754 | 0.81 | ALOX5 (0.54) | ADRB1MAPTCTSGCMA1ALOX5 | |
| SCHEMBL9795641 | 0.79 | ALOX5 (0.60) | ADRB1MAPTHSD17B10ALOX5 | |
| SCHEMBL9795608 | 0.78 | ALOX5 (0.40) | ALDH1A1MAPTNPSR1HSD17B10ALOX5 | |
| SCHEMBL9795696 | 0.77 | BPTF (0.35) | KMT2AMEN1ALDH1A1TSHRALOX5 | |
| SCHEMBL9795690 | 0.75 | ALOX5 (0.40) | ALDH1A1GAAMAPTCYP3A4CYP2C19 | |
| SCHEMBL9795576 | 0.75 | ALOX5 (0.54) | ADRB1KMT2AMEN1ALDH1A1CMA1 | |
| SCHEMBL9795578 | 0.75 | MMP13 (0.40) | KMT2AMEN1GAANPSR1CMA1 | |
| SCHEMBL9795810 | 0.74 | MGLL (0.42) | KMT2AMEN1ALDH1A1CYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023255-A | Triazine derivatives; inhibitors exzyme 5-lipoxygenase | GLAXO GROUP LIMITED (GB) | 1991-06-11 | — | — | US | disclosed |
| EP-0388165-A2 | Chemical compounds | GLAXO GROUP LIMITED (GB) | 1990-09-19 | — | — | EP | disclosed |