Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | ADAMTS5 | Q9UNA0 | 3/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 2/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9795750 | 0.86 | ALOX5 (0.35) | ALOX5ADAMTS5MMP2 | |
| SCHEMBL9795690 | 0.81 | ALOX5 (0.40) | ALOX5ALDH1A1DDB1CRBN | |
| SCHEMBL9795564 | 0.79 | ALOX5 (0.56) | ALOX5MEN1ALDH1A1KMT2A | |
| SCHEMBL9795544 | 0.78 | ALOX5 (0.56) | ALOX5ADAMTS5ALDH1A1 | |
| SCHEMBL9795576 | 0.78 | ALOX5 (0.54) | ALOX5MEN1ALDH1A1KMT2A | |
| SCHEMBL9795652 | 0.77 | ADRB1 (0.40) | TSHRALOX5MEN1ALDH1A1RAB9A | |
| SCHEMBL9795595 | 0.77 | ALOX5 (0.59) | ALOX5MMP2MEN1ALDH1A1KMT2A | |
| SCHEMBL9795578 | 0.75 | MMP13 (0.40) | ALOX5MEN1KMT2AMMP13 | |
| SCHEMBL9795754 | 0.75 | ALOX5 (0.54) | ALOX5RAB9A | |
| SCHEMBL28937147 | 0.73 | ALOX5 (0.62) | ALOX5RAD51 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023255-A | Triazine derivatives; inhibitors exzyme 5-lipoxygenase | GLAXO GROUP LIMITED (GB) | 1991-06-11 | — | — | US | disclosed |
| EP-0388165-A2 | Chemical compounds | GLAXO GROUP LIMITED (GB) | 1990-09-19 | — | — | EP | disclosed |