Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 13/20 | 0.53 |
| ▸ | CA1 | P00915 | 12/20 | 0.53 |
| ▸ | CA9 | Q16790 | 9/20 | 0.53 |
| ▸ | CA12 | O43570 | 7/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | CA7 | P43166 | 6/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.50 |
| ▸ | CA5A | P35218 | 2/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5453607 | 0.83 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1CA2CA1CA9 | |
| Water SCHEMBL10652196 | 0.82 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1CA2CA1CA9 | |
| SCHEMBL6500063 | 0.81 | CA2 (0.62) | ALDH1A1HSD17B10CA2CA1CA9 | |
| SCHEMBL7909439 | 0.79 | CA2 (0.61) | ALDH1A1CA2CA1CA9CA12 | |
| SCHEMBL3017227 | 0.79 | MMP2 (0.60) | ALDH1A1CA2CA1CA9CA12 | |
| SCHEMBL9231454 | 0.79 | ALDH1A1 (0.51) | ALDH1A1CA2CA1CA9CA12 | |
| SCHEMBL16734878 | 0.79 | CA2 (0.56) | ALDH1A1CA2CA1CA9CA12 | |
| SCHEMBL6804107 | 0.79 | CA1 (0.58) | ALDH1A1CA2CA1NPSR1 | |
| SCHEMBL3747089 | 0.79 | ADAMTS4 (0.58) | ALDH1A1L3MBTL1CA2CA1CA9 | |
| SCHEMBL2497635 | 0.79 | MMP2 (0.65) | ALDH1A1L3MBTL1CA2CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990015600-A2 | TREATMENT OF CHRONIC INFLAMMATORY JOINT DISEASE WITH ARYLSULFONAMIDES | A.H. ROBINS COMPANY, INCORPORATED (US) | 1990-12-27 | — | — | WO | claimed |
| US-4990523-A | Treatment of chronic inflammatory joint disease with arylsulfonamides | A. H. ROBINS COMPANY, INCORPORATED (US) | 1991-02-05 | — | — | US | disclosed |