SCHEMBL5453607

SCHEMBL5453607

CC(C)NS(=O)(=O)c1ccc(N)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.58
MMP1 P03956 2/20 0.57
MMP2 P08253 2/20 0.57
MMP9 P14780 2/20 0.57
MMP13 P45452 2/20 0.57
MMP3 P08254 1/20 0.57
MMP7 P09237 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.56
CA1 P00915 3/20 0.55
CA2 P00918 3/20 0.55
MMP8 P22894 1/20 0.55
TSHR P16473 2/20 0.53
DHFR P00374 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
SLC1A3 P43003 1/20 0.53
SLC1A2 P43004 1/20 0.53
SLC1A1 P43005 1/20 0.53
CA9 Q16790 3/20 0.52
CA12 O43570 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL10652196 0.98 ALDH1A1 (0.56) ALDH1A1MMP1MMP2MMP9MMP13
SCHEMBL2497635 0.94 MMP2 (0.65) ALDH1A1MMP1MMP2MMP9MMP13
SCHEMBL11246547 0.89 LMNA (0.53) ALDH1A1MMP1MMP2MMP9MMP13
SCHEMBL10785238 0.84 ALDH1A1 (0.54) ALDH1A1MMP1MMP2MMP9MMP13
SCHEMBL9231454 0.83 ALDH1A1 (0.51) ALDH1A1CA1CA2SMN1; SMN2CA9
SCHEMBL9796256 0.83 ALDH1A1 (0.54) ALDH1A1L3MBTL1CA1CA2CA9
SCHEMBL11936124 0.83 CA1 (0.51) ALDH1A1MMP1MMP2MMP9MMP13
SCHEMBL31219700 0.81 MMP1 (0.55) ALDH1A1MMP1MMP2MMP9MMP13
SCHEMBL6500063 0.81 CA2 (0.62) ALDH1A1MMP1MMP2MMP9MMP13
Hydrochloric Acid SCHEMBL11397823 0.80 ALDH1A1 (0.50) ALDH1A1MMP1MMP2MMP9MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105061362-A Preparation method of bentazon JIANGSU TAICANG AGRICULTURAL CHEMICALS CO LTD 2015-11-18 CN claimed
EP-4719413-A1 INHIBITORS OF CANINE JANUS KINASE AND USES THEREOF Animol Discovery, Inc. (US) 2026-04-08 EP disclosed
US-20260092070-A1 INHIBITORS OF CANINE JANUS KINASE AND USES THEREOF ANIMOL DISCOVERY INC (US) 2026-04-02 US disclosed
WO-2024246837-A1 INHIBITORS OF CANINE JANUS KINASE AND USES THEREOF ANIMOL DISCOVERY, INC. (US) 2024-12-05 WO disclosed
US-20240166635-A1 AMINOHETEROARYL KINASE INHIBITORS Allorion Therapeutics Inc 2024-05-23 US disclosed
CN-117794924-A Compounds useful as inhibitors of ATR kinase 苏州爱科百发生物医药技术有限公司 2024-03-29 CN disclosed
US-20230321096-A1 COMPOSITION FOR IMPROVING, PREVENTING OR TREATING MUSCULAR DISORDERS INCLUDING SULFONAMIDE-BASED COMPOUNDS THE INDUSTRY & ACADEMIC COOPERATION IN CHUNGNAM NATIONAL UNIVERSITY (IAC) (KR) 2023-10-12 US disclosed
US-20230321096-A1 COMPOSITION FOR IMPROVING, PREVENTING OR TREATING MUSCULAR DISORDERS INCLUDING SULFONAMIDE-BASED COMPOUNDS THE INDUSTRY & ACADEMIC COOPERATION IN CHUNGNAM NATIONAL UNIVERSITY (IAC) (KR) 2023-10-12 US disclosed
EP-4251613-A1 AMINOHETEROARYL KINASE INHIBITORS Allorion Therapeutics Inc. (US) 2023-10-04 EP disclosed
CN-116528869-A Amino heteroaryl kinase inhibitors 安锐生物医药科技(广州)有限公司 2023-08-01 CN disclosed
EP-0775110-B1 ARYLTHIO COMPOUNDS AS ANTIBACTERIAL AND ANTIVIRAL AGENTS WARNER LAMBERT CO (US) 2005-10-05 EP disclosed
WO-2005055941-A2 NOVEL M3 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS GLAXO GROUP LIMITED (GB) 2005-06-23 WO disclosed
EP-1451172-A1 THERAPEUTIC ISOQUINOLINE COMPOUNDS AstraZeneca AB (SE) 2004-09-01 EP disclosed
WO-2003037887-A1 THERAPEUTIC ISOQUINOLINE COMPOUNDS ASTRAZENECA AB (SE) 2003-05-08 WO disclosed
US-5668291-A THIOSUBSTITUTED PYRIDINES, TREATMENT OF AIDS AND HIV WARNER-LAMBERT COMPANY (US) 1997-09-16 US disclosed
US-5668178-A VIRICIDE, BACTERICIDE, HIV WARNER-LAMBERT COMPANY (US) 1997-09-16 US disclosed
EP-0775110-A1 ARYLTHIO COMPOUNDS AS ANTIBACTERIAL AND ANTIVIRAL AGENTS WARNER-LAMBERT COMPANY (US) 1997-05-28 EP disclosed
WO-1996004242-A1 ARYLTHIO COMPOUNDS AS ANTIBACTERIAL AND ANTIVIRAL AGENTS WARNER-LAMBERT COMPANY (US) 1996-02-15 WO disclosed
US-5463122-A Amido-phenylthiols or dithiobisbenzamides as bactericides, viricides, retrovirus antigrowth agents; AIDS WARNER-LAMBERT COMPANY (US) 1995-10-31 US disclosed
US-5342730-A With mordant and stripping layers EASTMAN KODAK COMPANY (US) 1994-08-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230321096-A1 COMPOSITION FOR IMPROVING, PREVENTING OR TREATING MUSCULAR DISORDERS INCLUDING SULFONAMIDE-BASED COMPOUNDS PHF20, MYH10, MYOF ALDH1A1 4400/4885MMP1 3472/4885MMP2 4299/4885
US-20260092070-A1 INHIBITORS OF CANINE JANUS KINASE AND USES THEREOF JAK1, JAK3, JAK2 ALDH1A1 1691/4885MMP1 746/4885MMP2 1375/4885
US-20240166635-A1 AMINOHETEROARYL KINASE INHIBITORS CDK2, CDK3, CDKL1 ALDH1A1 3274/4885MMP1 4015/4885MMP2 3084/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.