Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | TSPO | P30536 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5524626 | 0.85 | ALDH1A1 (0.48) | SMN1; SMN2TSHRGAAALDH1A1MAPT | |
| SCHEMBL7557302 | 0.80 | KMT2A (0.59) | SMN1; SMN2TSHRGAAALDH1A1MAPT | |
| SCHEMBL10529370 | 0.80 | TSHR (0.43) | SMN1; SMN2TSHRGAAALDH1A1MAPT | |
| SCHEMBL4213821 | 0.79 | ALDH1A1 (0.72) | SMN1; SMN2TSHRGAAALDH1A1MAPT | |
| SCHEMBL25708220 | 0.79 | ALDH1A1 (0.41) | SMN1; SMN2TSHRGAAALDH1A1MAPT | |
| SCHEMBL9796448 | 0.79 | ALDH1A1 (0.42) | SMN1; SMN2TSHRGAAALDH1A1MAPT | |
| SCHEMBL21953391 | 0.79 | ACLY (0.45) | SMN1; SMN2ALDH1A1MAPTKDM4EMCL1 | |
| SCHEMBL9796324 | 0.78 | LMNA (0.40) | SMN1; SMN2TSHRGAAALDH1A1MAPT | |
| SCHEMBL11288670 | 0.77 | GAA (0.50) | SMN1; SMN2TSHRGAAALDH1A1MAPT | |
| SCHEMBL20254406 | 0.77 | CSNK2A1 (0.38) | SMN1; SMN2TSHRGAAKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183391-A1 | BIOMASS DERIVED DIKETONES AS EFFICIENT VISIBLE LIGHT PHOTOINITIATORS | BOWLING GREEN STATE UNIVERSITY (US) | 2023-06-15 | — | — | US | disclosed |
| US-9920070-B2 | Spiro-oxazines, indolinones and preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2018-03-20 | — | — | US | disclosed |
| US-20170174706-A1 | SPIRO-OXAZINES, INDOLINONES AND PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-06-22 | — | — | US | disclosed |
| US-4997840-A | Quinolone sulphonates having antihypertensive activity | THE BOOTS COMPANY, PLC (GB) | 1991-03-05 | — | — | US | disclosed |
| WO-1989007593-A1 | THERAPEUTIC AGENTS | THE BOOTS COMPANY PLC (GB) | 1989-08-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170174706-A1 | SPIRO-OXAZINES, INDOLINONES AND PREPARATION THEREOF | NR3C2, AR, REN | SMN1; SMN2 1546/4885TSHR 2621/4885GAA 4737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.