Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9817615 | 0.81 | KMT2A (0.40) | KMT2AALDH1A1L3MBTL1TSHRGAA | |
| SCHEMBL9796527 | 0.77 | RAB9A (0.50) | KMT2AALDH1A1L3MBTL1GAAMAPT | |
| SCHEMBL9817692 | 0.77 | ALDH1A1 (0.40) | KMT2AALDH1A1L3MBTL1TSHRGAA | |
| SCHEMBL9796448 | 0.76 | ALDH1A1 (0.42) | KMT2AALDH1A1TSHRGAAMAPT | |
| SCHEMBL2544901 | 0.73 | ERCC5 (0.47) | KMT2AALDH1A1MAPTTP53SMN1; SMN2 | |
| SCHEMBL9796483 | 0.72 | KMT2A (0.32) | KMT2AALDH1A1 | |
| SCHEMBL9796279 | 0.72 | SMN1; SMN2 (0.47) | KMT2AALDH1A1TSHRGAAMAPT | |
| SCHEMBL5524626 | 0.72 | ALDH1A1 (0.48) | ALDH1A1TSHRGAAMAPTTP53 | |
| SCHEMBL2543077 | 0.72 | L3MBTL1 (0.56) | KMT2AALDH1A1L3MBTL1SMN1; SMN2HTT | |
| SCHEMBL5702466 | 0.72 | LMNA (0.43) | KMT2AALDH1A1L3MBTL1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997840-A | Quinolone sulphonates having antihypertensive activity | THE BOOTS COMPANY, PLC (GB) | 1991-03-05 | — | — | US | disclosed |
| EP-0330340-A1 | Therapeutic agents | The Boots Company PLC (GB) | 1989-08-30 | — | — | EP | disclosed |
| WO-1989007593-A1 | THERAPEUTIC AGENTS | THE BOOTS COMPANY PLC (GB) | 1989-08-24 | — | — | WO | disclosed |