Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 4/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.46 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL75753 | 0.79 | CES2 (0.52) | CYP2C9CYP2C19KMT2AMEN1CYP2D6 | |
| SCHEMBL9298853 | 0.79 | CES2 (0.52) | CYP2C9CYP2C19KMT2AMEN1CYP2D6 | |
| SCHEMBL467546 | 0.78 | HDAC4 (0.59) | CYP2C9CYP2C19KMT2AMEN1CYP2D6 | |
| SCHEMBL5220963 | 0.78 | SRC (0.61) | CYP2C9CYP2C19KMT2AMEN1CYP2D6 | |
| Hydrochloric Acid SCHEMBL75859 | 0.77 | CES2 (0.50) | CYP2C9CYP2C19KMT2AMEN1CYP2D6 | |
| SCHEMBL182527 | 0.77 | SRC (0.59) | CYP2C19KMT2ACYP2D6HDAC4HDAC7 | |
| SCHEMBL6366 | 0.76 | LMNA (0.62) | CYP2C9CYP2C19KMT2AMEN1CYP2D6 | |
| SCHEMBL6367 | 0.76 | LMNA (0.62) | CYP2C9CYP2C19KMT2AMEN1CYP2D6 | |
| Hydrochloric Acid SCHEMBL933980 | 0.76 | HDAC4 (0.57) | CYP2C9CYP2C19KMT2AMEN1CYP2D6 | |
| SCHEMBL2454097 | 0.76 | CYP2C9 (0.47) | CYP2C9CYP2C19KMT2AMEN1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5059542-A | Crosslinked complex of anionic polymer and synthetic polyamino acid | JURIDICAL FOUNDATION THE CHEMO-SERO-THERAPEUTIC RESEARCH INSTITUTE (JP) | 1991-10-22 | — | — | US | disclosed |