Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 5/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1660124 | 0.80 | LMNA (0.53) | PDE2ANQO2HSP90AA1HSP90AB1MEN1 | |
| SCHEMBL11056577 | 0.75 | LMNA (0.62) | MEN1KMT2AHTR2BTRPA1LMNA | |
| SCHEMBL4914691 | 0.75 | RORC (0.56) | PDE2AHSP90AA1HSP90AB1MEN1KMT2A | |
| SCHEMBL28186848 | 0.75 | PDE2A (0.47) | PDE2AHSP90AA1HSP90AB1MEN1KMT2A | |
| SCHEMBL19144710 | 0.70 | PDE2A (0.36) | PDE2A | |
| SCHEMBL11103299 | 0.70 | GABRA1 (0.50) | HSP90AA1HSP90AB1MEN1KMT2APTGS2 | |
| SCHEMBL4905932 | 0.69 | PDE2A (0.49) | PDE2ANQO2HSP90AA1HSP90AB1MEN1 | |
| SCHEMBL13855359 | 0.69 | PNMT (0.47) | HTR2BLMNASLC6A2ADRA1ANPSR1 | |
| SCHEMBL16960531 | 0.69 | PDE2A (0.49) | PDE2AHSP90AA1HSP90AB1HTR2BKDM4E | |
| SCHEMBL10507496 | 0.69 | GABRA1 (0.58) | MEN1KMT2AHTR2BLMNASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5064861-A | ACYLATED AMINE COMPOUNDS WHICH ARE USEFUL FUNGICIGAL AGENTS | ROUSSEL UCLAF (FR) | 1991-11-12 | — | — | US | disclosed |
| EP-0413807-A1 | ACYLATED POLYAMINES AND APPLICATIONS THEREOF AS VEGETABLE GROWTH REGULATORS | ROUSSEL-UCLAF (FR) | 1991-02-27 | — | — | EP | disclosed |
| WO-1990010386-A1 | ACYLATED POLYAMINES AND APPLICATIONS THEREOF AS VEGETABLE GROWTH REGULATORS | ROUSSEL-UCLAF (FR) | 1990-09-20 | — | — | WO | disclosed |
| EP-0376819-A1 | Acrylated polyamines, process for their preparation and their use as fungicides | ROUSSEL-UCLAF (FR) | 1990-07-04 | — | — | EP | disclosed |