Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.33 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30230568 | 0.82 | RAB9A (0.44) | EPHX2SMN1; SMN2POLBALDH1A1GAA | |
| SCHEMBL9488221 | 0.65 | NAPRT (0.37) | TSHRTP53EPHX1EPHX2CDK9 | |
| SCHEMBL6206540 | 0.62 | CRHBP (0.41) | KCNK3KCNK9ALDH1A1RAB9A | |
| SCHEMBL8833247 | 0.62 | — | — | |
| SCHEMBL10753033 | 0.62 | LMNA (0.37) | TSHRSMN1; SMN2NAPRTHSD17B10POLB | |
| SCHEMBL7153039 | 0.62 | CYP1A2 (0.53) | TSHRTP53EPHX1EPHX2CDK9 | |
| SCHEMBL17238789 | 0.61 | CA2 (0.31) | — | |
| SCHEMBL3488485 | 0.61 | — | — | |
| SCHEMBL2512897 | 0.59 | — | — | |
| SCHEMBL1663585 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5047132-A | Apparatus for catalytically reducing dioxygen using dirhodium complexes | UNIVERSITY OF HOUSTON (US) | 1991-09-10 | — | — | US | disclosed |
| US-4909911-A | Process for catalytically reducing dioxygen using dirhodium complexes | UNIVERSITY OF HOUSTON (US) | 1990-03-20 | — | — | US | disclosed |