Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | FES | P07332 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | MARK3 | P27448 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | FLT4 | P35916 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9800223 | 1.00 | FAAH (0.47) | FAAHKMT2APKMTRPV1HTT | |
| SCHEMBL8405578 | 0.89 | PKM (0.50) | KMT2APKMHTTLMNANFKB1 | |
| SCHEMBL7664472 | 0.85 | HTT (0.50) | KMT2APKMHTTLMNANFKB1 | |
| SCHEMBL7664478 | 0.85 | HTT (0.50) | KMT2APKMHTTLMNANFKB1 | |
| SCHEMBL9864923 | 0.85 | HTT (0.50) | KMT2APKMHTTLMNANFKB1 | |
| SCHEMBL8404147 | 0.84 | NAMPT (0.48) | KMT2APKMHTTLMNANFKB1 | |
| SCHEMBL7669071 | 0.83 | RIPK1 (0.45) | FAAHKMT2APKMTRPV1LMNA | |
| SCHEMBL9800116 | 0.83 | RIPK1 (0.45) | FAAHKMT2APKMTRPV1LMNA | |
| SCHEMBL7660006 | 0.82 | LMNA (0.47) | KMT2APKMHTTLMNANFKB1 | |
| SCHEMBL8406562 | 0.81 | HTT (0.48) | KMT2APKMHTTLMNANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5049571-A | Insecticides | CIBA-GEIGY CORPORATION (US) | 1991-09-17 | — | — | US | disclosed |
| US-4918086-A | PESTICIDES, INSECTICIDES | CIBA-GEIGY CORPORATION (US) | 1990-04-17 | — | — | US | disclosed |