Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 6/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7660006 | 0.95 | LMNA (0.47) | NAMPTHTTLMNANFKB1NFKB2 | |
| SCHEMBL8405578 | 0.88 | PKM (0.50) | NAMPTHTTLMNANFKB1NFKB2 | |
| SCHEMBL7664472 | 0.87 | HTT (0.50) | NAMPTHTTLMNANFKB1NFKB2 | |
| SCHEMBL9864923 | 0.87 | HTT (0.50) | NAMPTHTTLMNANFKB1NFKB2 | |
| SCHEMBL7664478 | 0.87 | HTT (0.50) | NAMPTHTTLMNANFKB1NFKB2 | |
| SCHEMBL7686987 | 0.86 | RIPK1 (0.48) | NAMPTHTTLMNANFKB1NFKB2 | |
| SCHEMBL9800218 | 0.84 | FAAH (0.47) | NAMPTHTTLMNANFKB1NFKB2 | |
| SCHEMBL9800223 | 0.84 | FAAH (0.47) | NAMPTHTTLMNANFKB1NFKB2 | |
| SCHEMBL9718704 | 0.83 | RIPK1 (0.47) | NAMPTHTTLMNANFKB1NFKB2 | |
| SCHEMBL7669212 | 0.83 | RIPK1 (0.47) | NAMPTHTTLMNANFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935981-A | INSECTICIDAL/MITICIDAL ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| US-5849768-A | α-unsaturated amines, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-12-15 | — | — | US | disclosed |