Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 5/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10494795 | 0.91 | MAPT (0.44) | MAPTTDP1CA2CA1CA9 | |
| SCHEMBL10494743 | 0.84 | CA2 (0.48) | MAPTCA2CA1CA9CA4 | |
| SCHEMBL9800377 | 0.82 | ADRB2 (0.46) | CA2LMNAMEN1KMT2ATP53 | |
| SCHEMBL9800340 | 0.80 | HTR1D (0.54) | CA2TP53ENPP1HTR2A | |
| SCHEMBL9800394 | 0.79 | ADRB2 (0.41) | CA2LMNAMEN1KMT2ATP53 | |
| SCHEMBL9800333 | 0.77 | NQO2 (0.42) | MAPTCA2MEN1KMT2ATP53 | |
| SCHEMBL9800355 | 0.77 | HTR6 (0.55) | HTR2A | |
| SCHEMBL9800426 | 0.77 | CYP19A1 (0.38) | CA2MEN1KMT2ATP53ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9800379 | 0.76 | HTR6 (0.54) | HTR2A | |
| Hydrochloric Acid SCHEMBL27673725 | 0.76 | ADRB2 (0.39) | CA2LMNAKMT2ATP53ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994483-A | 5-substituted-3-aminoalkyl indole derivatives for migraine | GLAXO GROUP LIMITED (GB) | 1991-02-19 | — | — | US | disclosed |