Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 6/20 | 0.64 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.64 |
| ▸ | AR | P10275 | 1/20 | 0.64 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.64 |
| ▸ | AXL | P30530 | 2/20 | 0.53 |
| ▸ | CLK1 | P49759 | 1/20 | 0.53 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | PLAT | P00750 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.46 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9447051 | 0.84 | PGR (0.60) | PGRNR3C1ARESR2AXL | |
| SCHEMBL9447018 | 0.83 | PGR (0.67) | PGRNR3C1ARESR2AXL | |
| SCHEMBL9446948 | 0.81 | PGR (0.67) | PGRNR3C1ARESR2AXL | |
| SCHEMBL9800673 | 0.80 | PGR (0.56) | PGRARTSHRKMT2A | |
| SCHEMBL1472100 | 0.79 | PGR (0.71) | PGRNR3C1ARESR2AXL | |
| SCHEMBL19878474 | 0.78 | KDR (0.72) | PGRNR3C1ARESR2AXL | |
| SCHEMBL10650464 | 0.77 | NR3C1 (0.60) | PGRNR3C1ARESR2AXL | |
| SCHEMBL4548881 | 0.73 | AXL (0.73) | AXLPLAUPLATKDRMAPK14 | |
| SCHEMBL9447154 | 0.73 | SLC40A1 (0.65) | PGRNR3C1ARESR2AXL | |
| SCHEMBL4460261 | 0.73 | BRAF (0.73) | PGRNR3C1ARESR2BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0261539-B1 | SUBSTITUTED PHENYL-SULPHON AMIDES | BAYER AG (DE) | 1991-03-06 | — | — | EP | disclosed |
| EP-0261539-A2 | Substituted phenyl-sulphon amides | BAYER AG (DE) | 1988-03-30 | — | — | EP | disclosed |