Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.32 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8566934 | 0.74 | LMNA (0.32) | CYP3A4LMNAALDH1A1KDM4E | |
| SCHEMBL3487989 | 0.73 | ALDH1A1 (0.39) | MEN1KMT2AMAPTCNR1CYP3A4 | |
| SCHEMBL1263274 | 0.71 | NPSR1 (0.36) | MEN1KMT2AMAPTCYP3A4LMNA | |
| SCHEMBL8614546 | 0.66 | ALDH1A1 (0.44) | MAPTCYP3A4MMP9LMNAALDH1A1 | |
| Albutoin SCHEMBL5053862 | 0.65 | KMT2A (1.00) | MEN1KMT2AMAPTL3MBTL1CYP3A4 | |
| Albutoin SCHEMBL35488 | 0.65 | KMT2A (1.00) | MEN1KMT2AMAPTL3MBTL1CYP3A4 | |
| SCHEMBL17294176 | 0.65 | ALDH1A1 (0.43) | CYP3A4MMP9LMNAALDH1A1KDM4E | |
| SCHEMBL1598182 | 0.62 | ALDH1A1 (0.44) | MEN1KMT2AMAPTL3MBTL1CNR1 | |
| SCHEMBL12706769 | 0.62 | ALDH1A1 (0.44) | MEN1KMT2AMAPTL3MBTL1CNR1 | |
| SCHEMBL12706812 | 0.62 | ALDH1A1 (0.44) | MEN1KMT2AMAPTL3MBTL1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0414815-A1 | BLOOD SUBSTITUTE | CRYOMEDICAL SCIENCES, INC. (US) | 1991-03-06 | — | — | EP | disclosed |
| WO-1989010746-A2 | BLOOD SUBSTITUTE | CRYOMEDICAL SCIENCES INC. (US) | 1989-11-16 | — | — | WO | disclosed |