Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1421315 | 0.91 | TSHR (0.48) | KCNN4TSHRALDH1A1PTPN1CA1 | |
| SCHEMBL9800786 | 0.91 | TSHR (0.48) | KCNN4TSHRALDH1A1PTPN1CA1 | |
| SCHEMBL1421122 | 0.91 | TSHR (0.48) | KCNN4TSHRALDH1A1PTPN1CA1 | |
| SCHEMBL15320774 | 0.91 | TSHR (0.48) | KCNN4TSHRALDH1A1PTPN1CA1 | |
| SCHEMBL10453463 | 0.91 | TSHR (0.48) | KCNN4TSHRALDH1A1PTPN1CA1 | |
| SCHEMBL3390346 | 0.89 | TSHR (0.50) | KCNN4TSHRALDH1A1PTPN1CA1 | |
| SCHEMBL30619668 | 0.84 | TSHR (0.55) | KCNN4TSHRALDH1A1PTPN1CA1 | |
| SCHEMBL11696796 | 0.82 | TSHR (0.52) | KCNN4TSHRALDH1A1PTPN1CA1 | |
| SCHEMBL673282 | 0.79 | LMNA (0.43) | CA1CA2LMNANR1H2NR1H3 | |
| SCHEMBL1421311 | 0.79 | KIF11 (0.56) | TSHRALDH1A1PTPN1MAPK1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553988-B2 | Method for producing coupling compound | SUMITOMO CHEMICAL COMPANY, LIMTED (JP) | 2009-06-30 | — | — | US | disclosed |
| EP-1439157-B1 | Method for producing Suzuki coupling compound catalysed by a nickel compound | SUMITOMO CHEMICAL CO (JP) | 2007-07-11 | — | — | EP | disclosed |
| US-7238832-B2 | Production method of a coupling compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-07-03 | — | — | US | disclosed |
| US-7217677-B2 | Method for producing coupling compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-05-15 | — | — | US | disclosed |
| US-20060281925-A1 | METHOD FOR PRODUCING COUPLING COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-12-14 | — | — | US | disclosed |
| EP-1449580-B1 | Production method of a cross-coupling compound from an alkyl halide and an organoboron compound | SUMITOMO CHEMICAL CO (JP) | 2005-12-28 | — | — | EP | disclosed |
| US-20040167364-A1 | Production method of a coupling compound | SUMITOMO CHEMICAL COMPANY, LIMITED | 2004-08-26 | — | — | US | disclosed |
| EP-1449580-A1 | Production method of a cross-coupling compound from an alkyl halide and an organoboron compound | Sumitomo Chemical Co.,Ltd. (JP) | 2004-08-25 | — | — | EP | disclosed |
| US-20040161404-A1 | Method for producing coupling compound | SUMITOMO CHEMICAL COMPANY, LIMITED | 2004-08-19 | — | — | US | disclosed |
| EP-1439157-A2 | Method for producing Suzuki coupling compound catalysed by a nickel compound | Sumitomo Chemical Co.,Ltd. (JP) | 2004-07-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040167364-A1 | Production method of a coupling compound | PYM1, BRIX1, CXCR1 | KCNN4 579/4885TSHR 447/4885ALDH1A1 3812/4885 |
| US-20060281925-A1 | METHOD FOR PRODUCING COUPLING COMPOUND | RPL22, CYP4A22, PYM1 | KCNN4 86/4885TSHR 711/4885ALDH1A1 3831/4885 |
| US-20040161404-A1 | Method for producing coupling compound | PYM1, MALT1, BET1 | KCNN4 262/4885TSHR 423/4885ALDH1A1 3550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.