SCHEMBL1421315

SCHEMBL1421315

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.48
ALDH1A1 P00352 1/20 0.48
PTPN1 P18031 2/20 0.38
LMNA P02545 1/20 0.38
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
CA5A P35218 1/20 0.37
CA9 Q16790 1/20 0.37
KCNN4 O15554 3/20 0.36
KIF11 P52732 1/20 0.36
ELANE P08246 1/20 0.33
MAPT P10636 1/20 0.33
THRB P10828 1/20 0.32
MAPK1 P28482 1/20 0.32
NR1H2 P55055 2/20 0.31
NR1H3 Q13133 2/20 0.31
PGK1 P00558 1/20 0.31
PGK2 P07205 1/20 0.31
PTPN5 P54829 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10453463 1.00 TSHR (0.48) TSHRALDH1A1PTPN1LMNACA1
SCHEMBL15320774 1.00 TSHR (0.48) TSHRALDH1A1PTPN1LMNACA1
SCHEMBL1421122 1.00 TSHR (0.48) TSHRALDH1A1PTPN1LMNACA1
SCHEMBL9800786 1.00 TSHR (0.48) TSHRALDH1A1PTPN1LMNACA1
SCHEMBL3390346 0.97 TSHR (0.50) TSHRALDH1A1PTPN1LMNACA1
SCHEMBL30619668 0.92 TSHR (0.55) TSHRALDH1A1PTPN1CA1CA2
Dimethylamine SCHEMBL4059229 0.91 KCNN4 (0.41) TSHRALDH1A1PTPN1LMNACA1
SCHEMBL11696796 0.90 TSHR (0.52) TSHRALDH1A1PTPN1CA1CA2
SCHEMBL673282 0.87 LMNA (0.43) LMNACA1CA2THRBNR1H2
SCHEMBL1421311 0.87 KIF11 (0.56) TSHRALDH1A1PTPN1KIF11MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120157105-A Method for defluorination of perfluoro and polyfluoroalkyl substances 中国科学技术大学 2025-06-17 CN claimed
CN-120157105-A Method for defluorination of perfluoro and polyfluoroalkyl substances 中国科学技术大学 2025-06-17 CN disclosed
US-20240122065-A1 METAL PATTERNING MATERIAL, AMINE COMPOUND, ELECTRONIC DEVICE, AND METHOD FOR FORMING METAL PATTERN TOSOH CORPORATION (JP) 2024-04-11 US disclosed
EP-4198163-A1 METAL PATTERNING MATERIAL, AMINE COMPOUND, ELECTRONIC DEVICE, AND METHOD FOR FORMING METAL PATTERN Tosoh Corporation (JP) 2023-06-21 EP disclosed
CN-116157382-A Material for metal patterning, amine compound, electronic device, and method for forming metal pattern 东曹株式会社 2023-05-23 CN disclosed
US-20110137063-A1 COMPOUNDS AND PROCESSES FOR PRODUCTION OF RADIOPHARMACEUTICALS BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2011-06-09 US disclosed
EP-2297070-A2 COMPOUNDS AND PROCESSES FOR PRODUCTION OF RADIOPHARMACEUTICALS Bayer Schering Pharma Aktiengesellschaft (DE) 2011-03-23 EP disclosed
WO-2010000409-A2 COMPOUNDS AND PROCESSES FOR PRODUCTION OF RADIOPHARMACEUTICALS BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2010-01-07 WO disclosed
EP-0510448-B1 Sulfonic acid esters of 2,4,6-tris-(2-hydroxy-ethoxy)-1,3,5-triazine, radiation-sensitive positive functioning mixture containing them and recording material CLARIANT GMBH (DE) 2000-03-01 EP disclosed
US-5981422-A PERFLUOROALKYLPHTHALOCYANINATO METAL COMPLEX OR 20-TETRAKIS-PENTAFLUOROPHENYL PORPHYRIN METAL COMPLEX USED AS CATALYST EXXON RESEARCH AND ENGINEERING CO. (US) 1999-11-09 US disclosed
US-5463082-A Fluorous multiphase systems EXXON RESEARCH AND ENGINEERING COMPANY (US) 1995-10-31 US disclosed
EP-0633062-A1 Fluorous multiphase catalyst or reagent systems, and processes using them EXXON RESEARCH AND ENGINEERING COMPANY (US) 1995-01-11 EP disclosed
US-5314786-A Positive-working radiation sensitive mixture comprising sulfonic acid esters of 2,4,6-tris-(2-hydroxyethoxy)-[1,3,5]triazine, and recording material containing these esters HOECHST AKTIENGESELLSCHAFT (DE) 1994-05-24 US disclosed
EP-0510441-A1 Positive-working radiation-sensitive composition and radiation-sensitive recording material produced therewith HOECHST AKTIENGESELLSCHAFT (DE) 1992-10-28 EP disclosed
EP-0510446-A1 Negative-working radiation-sensitive composition and radiation-sensitive recording material produced therewith HOECHST AKTIENGESELLSCHAFT (DE) 1992-10-28 EP disclosed
EP-0510447-A2 Negative-working radiation-sensitive composition and radiation-sensitive recording material produced therewith HOECHST AKTIENGESELLSCHAFT (DE) 1992-10-28 EP disclosed
EP-0510448-A1 Sulfonic acid esters of 2,4,6-tris-(2-hydroxy-ethoxy)-1,3,5-triazine, radiation-sensitive positive functioning mixture containing them and recording material HOECHST AKTIENGESELLSCHAFT (DE) 1992-10-28 EP disclosed
US-5113013-A Reacting a Sulfonyl Halide with Aromatic Halide IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-05-12 US disclosed
EP-0114359-B1 PROCESS FOR PREPARING PERFLUOROALKYL-SUBSTITUTED CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS HOECHST AKTIENGESELLSCHAFT (DE) 1985-07-31 EP disclosed
EP-0114359-A1 Process for preparing perfluoroalkyl-substituted carbocyclic or heterocyclic compounds HOECHST AKTIENGESELLSCHAFT (DE) 1984-08-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110137063-A1 COMPOUNDS AND PROCESSES FOR PRODUCTION OF RADIOPHARMACEUTICALS PFAS, PFKFB2, PFKFB1 TSHR 183/4885ALDH1A1 1252/4885PTPN1 4490/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.