Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 5/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | MAN2B1 | O00754 | 1/20 | 0.34 |
| ▸ | PAM | P19021 | 2/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 3/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10507583 | 0.83 | MAN2B1 (0.31) | NAAAMAN2B1 | |
| SCHEMBL9800835 | 0.82 | FAAH (0.35) | NAAAMAN2B1GBA1EPHX1 | |
| SCHEMBL10713568 | 0.80 | MAN2B1 (0.33) | NAAAMAN2B1GBA1 | |
| SCHEMBL11036205 | 0.77 | MAN2B1 (0.35) | NAAAMAN2B1GBA1 | |
| SCHEMBL9800800 | 0.74 | MAN2B1 (0.39) | NAAAMAN2B1GBA1 | |
| SCHEMBL10832279 | 0.73 | PLA2G2A (0.36) | — | |
| SCHEMBL11237700 | 0.71 | MAN2B1 (0.36) | NAAAMAN2B1GBA1 | |
| SCHEMBL10678300 | 0.71 | MAN2B1 (0.36) | NAAAMAN2B1GBA1 | |
| SCHEMBL11501324 | 0.70 | ACE (0.37) | NAAAMAN2B1 | |
| SCHEMBL11031748 | 0.70 | HCAR2 (0.40) | MAN2B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233607-B1 | [(2,2,2-Trichloroethoxy) methoxy]amine | E.R. Squibb & Sons, Inc. (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0170280-B1 | NOVEL INTERMEDIATES AND PROCESS FOR THE PREPARATION OF 3-ACYLAMINO-1-HYDROXY-2-AZETIDINONES | E.R. Squibb & Sons, Inc. (US) | 1990-12-05 | — | — | EP | disclosed |
| EP-0371004-A1 | [(1-Alkoxy-1-methyl)-ethoxy]-amines, their preparation and their use for the preparation of 3-acylamino-1-hydroxy-2-azetidinones | E.R. Squibb & Sons, Inc. (US) | 1990-05-30 | — | — | EP | disclosed |
| US-4633017-A | N-hydroxy protecting groups and process for the preparation of 3-acylamino-1-hydroxy-2-azetidinones | E. R. SQUIBB & SONS, INC. (US) | 1986-12-30 | — | — | US | disclosed |
| US-4581170-A | N-hydroxyl protecting groups and process and intermediates for the preparation of 3-acylamino-1-hydroxy-2-azetidinones | E. R. SQUIBB & SONS, INC. (US) | 1986-04-08 | — | — | US | disclosed |