Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAN2B1 | O00754 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 7/20 | 0.38 |
| ▸ | NAAA | Q02083 | 3/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | FUCA1 | P04066 | 6/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11237700 | 0.79 | MAN2B1 (0.36) | MAN2B1GBA1NAAAS1PR4S1PR1 | |
| SCHEMBL10678300 | 0.79 | MAN2B1 (0.36) | MAN2B1GBA1NAAAS1PR4S1PR1 | |
| SCHEMBL11036205 | 0.76 | MAN2B1 (0.35) | MAN2B1GBA1NAAA | |
| SCHEMBL9800835 | 0.75 | FAAH (0.35) | MAN2B1GBA1NAAA | |
| SCHEMBL9800830 | 0.74 | NAAA (0.34) | MAN2B1GBA1NAAA | |
| SCHEMBL10713568 | 0.73 | MAN2B1 (0.33) | MAN2B1GBA1NAAAS1PR4S1PR1 | |
| SCHEMBL11501324 | 0.72 | ACE (0.37) | MAN2B1NAAAS1PR4S1PR1S1PR3 | |
| SCHEMBL10832279 | 0.72 | PLA2G2A (0.36) | — | |
| SCHEMBL11031748 | 0.72 | HCAR2 (0.40) | MAN2B1 | |
| SCHEMBL11036202 | 0.71 | ACE (0.36) | MAN2B1GBA1S1PR4S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0170280-B1 | NOVEL INTERMEDIATES AND PROCESS FOR THE PREPARATION OF 3-ACYLAMINO-1-HYDROXY-2-AZETIDINONES | E.R. Squibb & Sons, Inc. (US) | 1990-12-05 | — | — | EP | claimed |
| EP-0170280-A1 | Novel intermediates and process for the preparation of 3-acylamino-1-hydroxy-2-azetidinones | E.R. Squibb & Sons, Inc. (US) | 1986-02-05 | — | — | EP | claimed |
| EP-0233607-B1 | [(2,2,2-Trichloroethoxy) methoxy]amine | E.R. Squibb & Sons, Inc. (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0170280-B1 | NOVEL INTERMEDIATES AND PROCESS FOR THE PREPARATION OF 3-ACYLAMINO-1-HYDROXY-2-AZETIDINONES | E.R. Squibb & Sons, Inc. (US) | 1990-12-05 | — | — | EP | disclosed |
| EP-0371004-A1 | [(1-Alkoxy-1-methyl)-ethoxy]-amines, their preparation and their use for the preparation of 3-acylamino-1-hydroxy-2-azetidinones | E.R. Squibb & Sons, Inc. (US) | 1990-05-30 | — | — | EP | disclosed |
| EP-0233607-A2 | [(2,2,2-Trichloroethoxy) methoxy]amine | E.R. Squibb & Sons, Inc. (US) | 1987-08-26 | — | — | EP | disclosed |
| EP-0233607-A2 | [(2,2,2-Trichloroethoxy) methoxy]amine | E.R. Squibb & Sons, Inc. (US) | 1987-08-26 | — | — | EP | disclosed |
| US-4633017-A | N-hydroxy protecting groups and process for the preparation of 3-acylamino-1-hydroxy-2-azetidinones | E. R. SQUIBB & SONS, INC. (US) | 1986-12-30 | — | — | US | disclosed |
| US-4581170-A | N-hydroxyl protecting groups and process and intermediates for the preparation of 3-acylamino-1-hydroxy-2-azetidinones | E. R. SQUIBB & SONS, INC. (US) | 1986-04-08 | — | — | US | disclosed |
| EP-0170280-A1 | Novel intermediates and process for the preparation of 3-acylamino-1-hydroxy-2-azetidinones | E.R. Squibb & Sons, Inc. (US) | 1986-02-05 | — | — | EP | disclosed |