Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAN2B1 | O00754 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 3/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11036202 | 0.81 | ACE (0.36) | ACEMEN1KMT2AMAN2B1S1PR4 | |
| SCHEMBL11036205 | 0.72 | MAN2B1 (0.35) | MAN2B1NAAA | |
| SCHEMBL9800800 | 0.72 | MAN2B1 (0.39) | MAN2B1NAAAS1PR4S1PR1S1PR3 | |
| SCHEMBL9800830 | 0.70 | NAAA (0.34) | MAN2B1NAAA | |
| SCHEMBL10678300 | 0.69 | MAN2B1 (0.36) | MAN2B1NAAAS1PR4S1PR1S1PR3 | |
| SCHEMBL22128248 | 0.69 | RAB9A (0.36) | ACE | |
| SCHEMBL22128246 | 0.69 | RAB9A (0.36) | ACE | |
| SCHEMBL11237700 | 0.69 | MAN2B1 (0.36) | MAN2B1NAAAS1PR4S1PR1S1PR3 | |
| SCHEMBL9800835 | 0.69 | FAAH (0.35) | MAN2B1NAAA | |
| SCHEMBL22155675 | 0.68 | ITGB3 (0.35) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4195021-A | 1,3-Disubstituted 2-azetidinone antibitotics | ELI LILLY AND COMPANY (US) | 1980-03-25 | — | — | US | disclosed |
| EP-0001715-A2 | Azetidinone antibiotics and their pharmaceutical formulations and use | ELI LILLY AND COMPANY (US) | 1979-05-02 | — | — | EP | disclosed |