Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.43 |
| ▸ | MYLK | Q15746 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PRKCG | P05129 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985327 | 0.76 | THRB (0.56) | THRBALDH1A1CYP3A4CA1CA2 | |
| SCHEMBL9633520 | 0.74 | CYP3A4 (0.44) | THRBALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL12697427 | 0.73 | PRKCE (0.46) | THRBALDH1A1PRKCEMYLKRECQL | |
| SCHEMBL11316537 | 0.73 | CYP3A4 (0.46) | ALDH1A1MAPTCYP3A4CA1CA2 | |
| SCHEMBL29589540 | 0.73 | CYP3A4 (0.47) | THRBALDH1A1RECQLMAPTTDP1 | |
| SCHEMBL25189805 | 0.73 | PRKCI (0.56) | THRBALDH1A1RECQLKMT2AMEN1 | |
| SCHEMBL93999 | 0.72 | THRB (1.00) | THRBALDH1A1RECQLKMT2AMEN1 | |
| SCHEMBL9800891 | 0.72 | ALDH1A1 (0.38) | ALDH1A1PRKCEKMT2AMEN1MAPT | |
| SCHEMBL10495541 | 0.71 | GPR35 (0.54) | ALDH1A1PRKCEMYLKRECQLKMT2A | |
| SCHEMBL655140 | 0.71 | THRB (0.68) | THRBALDH1A1RECQLMAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59216855-A | — | — | None | — | — | JP | disclosed |
| EP-0116409-B1 | FUNGICIDAL ANILINE DERIVATIVES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-03-13 | — | — | EP | disclosed |
| US-4647584-A | Fungicidal aniline derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-03-03 | — | — | US | disclosed |
| US-4647583-A | Fungicidal aniline derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-03-03 | — | — | US | disclosed |
| JP-S59216855-A | 2-HALO-4-AMINO-6-SUBSTITUTED PHENOL AND ITS PREPARATION | SUMITOMO CHEM CO LTD | 1984-12-06 | — | — | JP | disclosed |
| EP-0116409-A2 | Fungicidal aniline derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-08-22 | — | — | EP | disclosed |