Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7536495 | 1.00 | PTGS2 (0.46) | PTGS2NLRP3ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL5533366 | 0.88 | GABRA1 (0.44) | NLRP3ALDH1A1HTTKDM4EMAPT | |
| SCHEMBL429150 | 0.83 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL13458993 | 0.79 | LMNA (0.38) | NLRP3ALDH1A1HTTSMN1; SMN2MEN1 | |
| SCHEMBL2868352 | 0.78 | SCN5A (0.50) | PTGS2NLRP3ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL16480275 | 0.78 | PTGS2 (0.58) | PTGS2NLRP3ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL11171249 | 0.78 | PTGS2 (0.50) | PTGS2NLRP3ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL710531 | 0.76 | KCNH2 (0.51) | PTGS2NLRP3ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL9840547 | 0.76 | TSHR (0.39) | PTGS2ALDH1A1HTTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL2868350 | 0.76 | PTGS2 (0.49) | PTGS2NLRP3ALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5025096-A | Preparation of indole and indole derivatives | MINE SAFETY APPLIANCES COMPANY (US) | 1991-06-18 | — | — | US | disclosed |