Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.57 |
| ▸ | CES1 | P23141 | 2/20 | 0.57 |
| ▸ | FNTA | P49354 | 1/20 | 0.48 |
| ▸ | FNTB | P49356 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GSR | P00390 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PAM | P19021 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27657958 | 0.89 | CES2 (0.53) | CES2CES1FNTAFNTBAKR1B1 | |
| SCHEMBL28267077 | 0.84 | CES2 (0.47) | CES2CES1FNTAFNTBAKR1B1 | |
| SCHEMBL628245 | 0.83 | CES2 (0.54) | CES2CES1FNTAFNTBAKR1B1 | |
| SCHEMBL27471961 | 0.79 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1MAPK1HTTKMT2A | |
| SCHEMBL339795 | 0.76 | CES1 (0.67) | CES2CES1FNTAFNTBAKR1B1 | |
| SCHEMBL28704435 | 0.75 | KEAP1 (0.46) | ALDH1A1L3MBTL1MAPK1SMN1; SMN2HTT | |
| SCHEMBL574185 | 0.75 | CES1 (1.00) | CES2CES1FNTAFNTBAKR1B1 | |
| SCHEMBL5691685 | 0.75 | CES1 (0.64) | CES2CES1FNTAFNTBAKR1B1 | |
| SCHEMBL11044523 | 0.75 | CES1 (0.64) | CES2CES1FNTAFNTBAKR1B1 | |
| Methyl Phenylpyruvate SCHEMBL237446 | 0.75 | CES2 (0.64) | CES2CES1FNTAFNTBAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5025096-A | Preparation of indole and indole derivatives | MINE SAFETY APPLIANCES COMPANY (US) | 1991-06-18 | — | — | US | disclosed |