Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.30 |
| ▸ | DRD3 | P35462 | 2/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9801622 | 0.84 | TSHR (0.33) | — | |
| SCHEMBL9801597 | 0.80 | HTR1A (0.36) | DRD2SIGMAR1HTR2A | |
| SCHEMBL9801148 | 0.80 | ALDH1A1 (0.39) | — | |
| SCHEMBL9802015 | 0.80 | ALOX15 (0.50) | SIGMAR1 | |
| SCHEMBL7902209 | 0.78 | HTR1A (0.33) | DRD2SIGMAR1HTR2A | |
| SCHEMBL9801943 | 0.77 | KEAP1 (0.41) | SIGMAR1 | |
| SCHEMBL15318699 | 0.77 | HSD11B1 (0.37) | — | |
| SCHEMBL9801159 | 0.77 | TSHR (0.33) | — | |
| SCHEMBL20003030 | 0.73 | — | — | |
| SCHEMBL15316721 | 0.72 | KDM1A (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017106607-A1 | POLYCYCLIC TLR7/8 ANTAGONISTS AND USE THEREOF IN THE TREATMENT OF IMMUNE DISORDERS | MERCK PATENT GMBH (DE) | 2017-06-22 | — | — | WO | disclosed |
| US-4992150-A | Telomer with alpha-olefin;oil and fuel additive | NIPPON OIL CO, LTD. (JP) | 1991-02-12 | — | — | US | disclosed |