Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313225 | 0.84 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL9520586 | 0.82 | ACHE (0.54) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL9802580 | 0.81 | MAP1LC3B (0.47) | ALDH1A1MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL6958079 | 0.72 | KDM4E (0.67) | ALDH1A1MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL9802431 | 0.70 | MAPT (0.39) | ALDH1A1MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL6113040 | 0.70 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL5713189 | 0.70 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2AKDM4ERAB9A | |
| Hydrochloric Acid SCHEMBL9802239 | 0.69 | MAPT (0.38) | ALDH1A1MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL9802388 | 0.69 | CHRNB2 (0.34) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL9523559 | 0.69 | MAOB (0.56) | ALDH1A1KDM4ELMNAMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994486-A | Neurological disorders | ABBOTT LABORATORIES (US) | 1991-02-19 | — | — | US | disclosed |