Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B13 | Q7Z5P4 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24664732 | 0.83 | RGS4 (0.39) | HSD17B13ALDH1A1CYP2D6CYP2C9ALOX15 | |
| SCHEMBL24205292 | 0.80 | HSP90AA1 (0.42) | ALDH1A1KDM4EMAPTPOLBMAPK1 | |
| SCHEMBL2297694 | 0.79 | LPO (0.40) | HSD17B13ALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL24665500 | 0.78 | HSD17B13 (0.44) | HSD17B13ALDH1A1 | |
| SCHEMBL21911678 | 0.78 | ALDH1A1 (0.39) | HSD17B13ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL10376057 | 0.77 | PIK3CD (0.34) | ALDH1A1KDM4EGAAMAPTGFER | |
| SCHEMBL29499333 | 0.75 | ADORA1 (0.44) | ALDH1A1MAPTMAPK1CYP2D6CYP2C9 | |
| SCHEMBL7274815 | 0.75 | PDE4A (0.39) | HSD17B10 | |
| SCHEMBL4481771 | 0.74 | HSD17B13 (0.36) | HSD17B13CYP2D6CYP2C9ALOX15CYP2C19 | |
| SCHEMBL16130822 | 0.74 | PKM (0.33) | ALDH1A1KDM4EPOLBGSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230027396-A1 | EXCIPIENT COMPOUNDS FOR BIOPOLYMER FORMULATIONS | COMERA LIFE SCIENCES, INC. | 2023-01-26 | — | — | US | claimed |
| EP-4065166-A1 | EXCIPIENT COMPOUNDS FOR BIOPOLYMER FORMULATIONS | Comera Life Sciences, Inc. (US) | 2022-10-05 | — | — | EP | claimed |
| WO-2021108427-A1 | EXCIPIENT COMPOUNDS FOR BIOPOLYMER FORMULATIONS | REFORM BIOLOGICS, LLC (US) | 2021-06-03 | — | — | WO | claimed |
| WO-2024059665-A1 | DIMERIC COMPOUNDS AS INHIBITORS OF GLYCOGEN SYNTHASE 1 (GYS1) AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2024-03-21 | — | — | WO | disclosed |
| WO-2023091370-A1 | EXCIPIENT COMPOUNDS FOR BIOPOLYMER FORMULATIONS | COMERA LIFE SCIENCES, INC. (US) | 2023-05-25 | — | — | WO | disclosed |
| US-20230027396-A1 | EXCIPIENT COMPOUNDS FOR BIOPOLYMER FORMULATIONS | COMERA LIFE SCIENCES, INC. | 2023-01-26 | — | — | US | disclosed |
| EP-4065166-A1 | EXCIPIENT COMPOUNDS FOR BIOPOLYMER FORMULATIONS | Comera Life Sciences, Inc. (US) | 2022-10-05 | — | — | EP | disclosed |
| WO-2022198196-A1 | INHIBITORS OF GLYCOGEN SYNTHASE 1 (GYS1) AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2022-09-22 | — | — | WO | disclosed |
| US-20210379185-A1 | EXCIPIENT COMPOUNDS FOR PROTEIN PROCESSING | COMERA LIFE SCIENCES, INC. | 2021-12-09 | — | — | US | disclosed |
| EP-3886909-A1 | EXCIPIENT COMPOUNDS FOR PROTEIN PROCESSING | ReForm Biologics, Inc. (US) | 2021-10-06 | — | — | EP | disclosed |
| WO-2021108427-A1 | EXCIPIENT COMPOUNDS FOR BIOPOLYMER FORMULATIONS | REFORM BIOLOGICS, LLC (US) | 2021-06-03 | — | — | WO | disclosed |
| WO-2020112855-A1 | EXCIPIENT COMPOUNDS FOR PROTEIN PROCESSING | REFORM BIOLOGICS, LLC (US) | 2020-06-04 | — | — | WO | disclosed |
| WO-2013013013-A2 | COMPOSITIONS AND METHODS FOR PRODUCING MODIFIED GLYCOPROTEINS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2013-01-24 | — | — | WO | disclosed |
| EP-0299413-B1 | New tetramethyl-cis-diaza-bicyclo[4.2.0]octane-3,5-dione derivatives having a differentiation-inducing activity | MEIJI SEIKA KAISHA LTD. (JP) | 1991-03-20 | — | — | EP | disclosed |
| US-4939156-A | Antitumor agents | MEIJI SEIKA KAISHA, LTD. (JP) | 1990-07-03 | — | — | US | disclosed |
| EP-0299413-A1 | New tetramethyl-cis-diaza-bicyclo[4.2.0]octane-3,5-dione derivatives having a differentiation-inducing activity | MEIJI SEIKA KAISHA LTD. (JP) | 1989-01-18 | — | — | EP | disclosed |
| US-4171429-A | Pyrimidine to pyrimidine transformation process | RESEARCH CORPORATION (US) | 1979-10-16 | — | — | US | disclosed |