SCHEMBL9804574

SCHEMBL9804574

C=CCc1c(CC)c(Cc2ccccc2)c(O)c(Cc2ccccc2)c1C1CCCCC1

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.33
CETP P11597 1/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
KMT2A Q03164 1/20 0.32
PLA2G2A P14555 1/20 0.31
KDM4E B2RXH2 1/20 0.31
GLA P06280 1/20 0.31
GAA P10253 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9804571 0.86 L3MBTL1 (0.39) L3MBTL1CETPMEN1ALDH1A1KMT2A
SCHEMBL31545835 0.68 NQO1 (0.38) L3MBTL1ALDH1A1KDM4EGAASMN1; SMN2
SCHEMBL1499291 0.67 GABRA1 (0.38) MEN1ALDH1A1KMT2AKDM4E
SCHEMBL10870748 0.66 KDM4E (0.43) ALDH1A1KDM4EGLAGAASMN1; SMN2
SCHEMBL4527677 0.65 GABRA1 (0.38)
Allylbenzene SCHEMBL793624 0.65 SLC18A3 (0.45) MEN1ALDH1A1KMT2A
SCHEMBL8586743 0.65 KDM4E (0.33) MEN1ALDH1A1KMT2AKDM4E
SCHEMBL9618801 0.65 BCL2 (0.44) MEN1KMT2A
SCHEMBL31544863 0.64 IDH1 (0.49) ALDH1A1
SCHEMBL11837416 0.64 NUDT1 (0.39) MEN1ALDH1A1KMT2AKDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0186255-B1 PROCESS FOR PREPARING BENZYL SUBSTITUTED PHENOLS, DIBENZYLPHENOLIC COMPOUNDS, AND THE ANTIOXIDANT USE OF SUCH PHENOLS ETHYL CORPORATION (US) 1991-04-10 EP disclosed
EP-0186255-A2 Process for preparing benzyl substituted phenols, dibenzylphenolic compounds, and the antioxidant use of such phenols ETHYL CORPORATION (US) 1986-07-02 EP disclosed