Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8973198 | 0.79 | ALDH1A1 (0.42) | KMT2AMEN1ALDH1A1VCAM1NPBWR1 | |
| SCHEMBL8972886 | 0.76 | ALDH1A1 (0.40) | KMT2AMEN1ALDH1A1VCAM1NPBWR1 | |
| SCHEMBL9734100 | 0.70 | ALDH1A1 (0.56) | ALDH1A1TDP1GAASMN1; SMN2TSHR | |
| SCHEMBL28472152 | 0.70 | ALDH1A1 (0.56) | KMT2AMEN1ALDH1A1VCAM1TDP1 | |
| SCHEMBL14058836 | 0.70 | CA2 (0.58) | ALDH1A1VCAM1TDP1POLBLMNA | |
| SCHEMBL8973579 | 0.70 | ALDH1A1 (0.56) | KMT2AMEN1ALDH1A1VCAM1TDP1 | |
| SCHEMBL28470101 | 0.69 | ALDH1A1 (0.54) | KMT2AMEN1ALDH1A1TDP1GAA | |
| SCHEMBL9735773 | 0.64 | ALDH1A1 (0.69) | KMT2AMEN1ALDH1A1TDP1POLB | |
| SCHEMBL8668528 | 0.64 | TSHR (0.66) | KMT2AMEN1ALDH1A1TDP1LMNA | |
| SCHEMBL9734521 | 0.63 | ALDH1A1 (0.67) | KMT2AMEN1ALDH1A1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5004751-A | Antidiabetic agents; aldoe reductase inhibitors | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1991-04-02 | — | — | US | disclosed |