Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 5/20 | 0.44 |
| ▸ | CDC25A | P30304 | 1/20 | 0.44 |
| ▸ | CDC25C | P30307 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9806587 | 0.87 | MAPT (0.51) | PTGS2MAPTALOX15ALDH1A1KMT2A | |
| SCHEMBL9806492 | 0.84 | MAPT (0.54) | PTGS2MAPTALOX15ALDH1A1KMT2A | |
| SCHEMBL9806505 | 0.79 | PTGS2 (0.48) | PTGS2MAPTALOX15ALDH1A1KMT2A | |
| SCHEMBL9806498 | 0.76 | PTGS2 (0.46) | PTGS2MAPTALOX15ALDH1A1KMT2A | |
| SCHEMBL19065779 | 0.76 | MAPT (0.79) | PTGS2MAPTALOX15ALDH1A1KMT2A | |
| SCHEMBL9806533 | 0.75 | MAPT (0.52) | PTGS2MAPTALOX15ALDH1A1KMT2A | |
| SCHEMBL9806503 | 0.75 | CDC25B (0.47) | PTGS2MAPTALOX15ALDH1A1KMT2A | |
| SCHEMBL7025322 | 0.74 | MAPT (0.61) | PTGS2MAPTALOX15ALDH1A1KMT2A | |
| SCHEMBL9806523 | 0.73 | MAPT (0.50) | PTGS2MAPTALOX15ALDH1A1KMT2A | |
| SCHEMBL9806500 | 0.73 | MAPT (0.52) | PTGS2MAPTALOX15ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017604-A | Antiinflammatory | WARNER-LAMBERT COMPANY (US) | 1991-05-21 | — | — | US | claimed |