Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 16/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.36 |
| ▸ | GCK | P35557 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulazuril SCHEMBL8602617 | 0.86 | PTGS2 (0.38) | PTGS2PTGS1GCKCYP11B1CYP11B2 | |
| SCHEMBL9806729 | 0.84 | NPBWR1 (0.33) | PTGS2 | |
| SCHEMBL9806752 | 0.82 | PTGS2 (0.36) | PTGS2PTGS1GCKCYP11B1CYP11B2 | |
| SCHEMBL9501110 | 0.76 | PTGS2 (0.39) | PTGS2PTGS1GCKCYP11B1CYP11B2 | |
| SCHEMBL9501824 | 0.71 | LMNA (0.31) | — | |
| SCHEMBL9503269 | 0.70 | NPBWR1 (0.35) | — | |
| SCHEMBL9806719 | 0.68 | PTGS2 (0.38) | PTGS2PTGS1GCKCYP11B1CYP11B2 | |
| SCHEMBL15904417 | 0.67 | PTGS2 (0.49) | PTGS2PTGS1CYP11B1CYP11B2 | |
| SCHEMBL9501104 | 0.67 | THRB (0.60) | — | |
| SCHEMBL11649861 | 0.64 | PTGS2 (0.52) | PTGS2PTGS1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215354-B1 | SUBSTITUTED 2-PHENYL-HEXAHYDRO-1,2,4-TRIAZINE-3,5-DIONES, PROCESS FOR THEIR PREPARATION, PRODUCTS CONTAINING THEM AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-04-24 | — | — | EP | disclosed |
| US-4782056-A | COCCIDIOSTATICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-11-01 | — | — | US | disclosed |