Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 17/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.39 |
| ▸ | GCK | P35557 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9501834 | 0.84 | LMNA (0.32) | — | |
| SCHEMBL9504425 | 0.83 | NPBWR1 (0.35) | PTGS2 | |
| SCHEMBL9806719 | 0.82 | PTGS2 (0.38) | PTGS2PTGS1GCKCYP11B1CYP11B2 | |
| Sulazuril SCHEMBL8602617 | 0.79 | PTGS2 (0.38) | PTGS2PTGS1GCKCYP11B1CYP11B2 | |
| SCHEMBL9502409 | 0.77 | THRB (0.44) | — | |
| SCHEMBL9806715 | 0.76 | PTGS2 (0.36) | PTGS2PTGS1GCKCYP11B1CYP11B2 | |
| SCHEMBL9806752 | 0.75 | PTGS2 (0.36) | PTGS2PTGS1GCKCYP11B1CYP11B2 | |
| SCHEMBL15904417 | 0.70 | PTGS2 (0.49) | PTGS2PTGS1CYP11B1CYP11B2 | |
| SCHEMBL9500876 | 0.70 | THRB (0.38) | PTGS2 | |
| SCHEMBL9501104 | 0.70 | THRB (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154885-B1 | SUBSTITUTED 2-PHENYL-HEXAHYDRO-1,2,4-TRIAZINE-2,5-DIONES, METHOD FOR THEIR PREPARATION, THEIR USE AS VETERINARY MEDICINES AND FOR COMBATING PROTOZOES | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-01-18 | — | — | EP | claimed |
| US-5188832-A | Triazine-dione compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-02-23 | — | — | US | disclosed |
| EP-0215354-B1 | SUBSTITUTED 2-PHENYL-HEXAHYDRO-1,2,4-TRIAZINE-3,5-DIONES, PROCESS FOR THEIR PREPARATION, PRODUCTS CONTAINING THEM AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-04-24 | — | — | EP | disclosed |
| EP-0383285-A2 | Agent against fish and insect parasites | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-08-22 | — | — | EP | disclosed |
| EP-0154885-B1 | SUBSTITUTED 2-PHENYL-HEXAHYDRO-1,2,4-TRIAZINE-2,5-DIONES, METHOD FOR THEIR PREPARATION, THEIR USE AS VETERINARY MEDICINES AND FOR COMBATING PROTOZOES | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-01-18 | — | — | EP | disclosed |
| US-4782056-A | COCCIDIOSTATICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-11-01 | — | — | US | disclosed |
| EP-0215354-A2 | Substituted 2-phenyl-hexahydro-1,2,4-triazine-3,5-diones, process for their preparation, products containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-25 | — | — | EP | disclosed |