Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | ALDH1A3 | P47895 | 5/20 | 0.53 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952189 | 1.00 | ALDH1A1 (0.64) | ALDH1A1ALDH1A3ALDH3A1CYP3A4CYP2A6 | |
| SCHEMBL29955168 | 0.82 | ALDH1A1 (0.64) | ALDH1A1ALDH1A3ALDH3A1CYP2A6HSD17B10 | |
| SCHEMBL276473 | 0.82 | ALDH1A1 (0.64) | ALDH1A1ALDH1A3ALDH3A1CYP2A6HSD17B10 | |
| Ethane SCHEMBL2153562 | 0.80 | ALDH1A1 (0.61) | ALDH1A1ALDH1A3ALDH3A1CYP2A6HSD17B10 | |
| SCHEMBL3927881 | 0.79 | ALDH1A1 (0.46) | ALDH1A1ALDH1A3CYP3A4CYP2A6HSD17B10 | |
| SCHEMBL10870983 | 0.79 | CYP3A4 (0.48) | ALDH1A1ALDH1A3CYP3A4PTGS2SMN1; SMN2 | |
| SCHEMBL48577 | 0.78 | ALDH1A1 (1.00) | ALDH1A1ALDH1A3ALDH3A1CYP2A6HSD17B10 | |
| SCHEMBL29364412 | 0.78 | ALDH1A1 (1.00) | ALDH1A1ALDH1A3ALDH3A1CYP2A6HSD17B10 | |
| SCHEMBL98097 | 0.78 | CYP2A6 (0.52) | ALDH1A1ALDH1A3CYP2A6HSD17B10TSHR | |
| SCHEMBL29350085 | 0.78 | CYP2A6 (0.52) | ALDH1A1ALDH1A3CYP2A6HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 225 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240033318-A1 | PEPTIDYL INHIBITORS OF CALCINEURIN-NFAT INTERACTION | OHIO STATE INNOVATION FOUNDATION | 2024-02-01 | — | — | US | claimed |
| US-11576946-B2 | Peptidyl inhibitors of calcineurin-NFAT interaction | OHIO STATE INNOVATION FOUNDATION (US) | 2023-02-14 | — | — | US | claimed |
| US-20210169966-A1 | PEPTIDYL INHIBITORS OF CALCINEURIN-NFAT INTERACTION | OHIO STATE INNOVATION FOUNDATION | 2021-06-10 | — | — | US | claimed |
| EP-3749365-A2 | PEPTIDYL INHIBITORS OF CALCINEURIN-NFAT INTERACTION | Ohio State Innovation Foundation (US) | 2020-12-16 | — | — | EP | claimed |
| US-RE48335-E1 | Polymyxin derivatives as antimicrobial compounds | MONASH UNIVERSITY (AU) | 2020-12-01 | — | — | US | claimed |
| CN-106414480-B | Polymyxin derivatives as antimicrobial compounds | 莫纳什大学 | 2020-08-04 | — | — | CN | claimed |
| WO-2019148194-A2 | PEPTIDYL INHIBITORS OF CALCINEURIN-NFAT INTERACTION | OHIO STATE INNOVATION FOUNDATION (US) | 2019-08-01 | — | — | WO | claimed |
| US-20170137469-A1 | POLYMYXIN DERIVATIVES AS ANTIMICROBIAL COMPOUNDS | MONASH UNIVERSITY (AU) | 2017-05-18 | — | — | US | claimed |
| EP-3126376-A1 | POLYMYXIN DERIVATIVES AS ANTIMICROBIAL COMPOUNDS | Monash University (AU) | 2017-02-08 | — | — | EP | claimed |
| WO-2015149131-A1 | POLYMYXIN DERIVATIVES AS ANTIMICROBIAL COMPOUNDS | MONASH UNIVERSITY (AU) | 2015-10-08 | — | — | WO | claimed |
| EP-4103557-B1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2026-02-18 | — | — | EP | disclosed |
| US-12502378-B2 | Monoacylglycerol lipase modulators for use in autism spectrum disorders | JANSSEN PHARMACEUTICA NV (BE) | 2025-12-23 | — | — | US | disclosed |
| EP-4384165-B1 | MONOACYLGLYCEROL LIPASE MODULATORS FOR USE IN AUTISM SPECTRUM DISORDERS | JANSSEN PHARMACEUTICA NV (BE) | 2025-07-09 | — | — | EP | disclosed |
| EP-4516118-A2 | USE OF AMBOCENIDE® FOR REINFORCING A LILY OF THE VALLEY NOTE | Symrise AG (DE) | 2025-03-05 | — | — | EP | disclosed |
| EP-3665163-B1 | USE OF AMBROCENIDE® FOR ENHANCING THE FRAGRANCE OF LILLIES OF THE VALLEY | SYMRISE AG (DE) | 2024-12-25 | — | — | EP | disclosed |
| US-4153719-A | Aromatic diketones | STERLING DRUG INC. (US) | 1979-05-08 | — | — | US | disclosed |
| US-RE29358-E | ANTI-MALARIA AND ANTI-TUBERCULOSIS AGENTS | AMERICAN CYANAMID COMPANY (US) | 1977-08-16 | — | — | US | disclosed |
| US-4024274-A | Benzylamine derivatives and process for preparing them | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-05-17 | — | — | US | disclosed |
| US-4002660-A | ANTIBACTERIAL AGENTS | MORTON-NORWICH PRODUCTS, INC. (US) | 1977-01-11 | — | — | US | disclosed |
| US-3962219-A | DISTYRYL-BENZOBISOXAZOLES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12502378-B2 | Monoacylglycerol lipase modulators for use in autism spectrum disorders | LIPC, LPL, MGLL | ALDH1A1 266/4885ALDH1A3 517/4885ALDH3A1 432/4885 |
| US-20210169966-A1 | PEPTIDYL INHIBITORS OF CALCINEURIN-NFAT INTERACTION | CHP1, NFATC1, PPP3R1 | ALDH1A1 4853/4885ALDH1A3 4541/4885ALDH3A1 4549/4885 |
| US-20240033318-A1 | PEPTIDYL INHIBITORS OF CALCINEURIN-NFAT INTERACTION | CHP1, NFATC1, PPP3R1 | ALDH1A1 4851/4885ALDH1A3 4540/4885ALDH3A1 4541/4885 |
| US-11576946-B2 | Peptidyl inhibitors of calcineurin-NFAT interaction | CHP1, NFATC1, PPP3R1 | ALDH1A1 4851/4885ALDH1A3 4540/4885ALDH3A1 4541/4885 |
| US-20170137469-A1 | POLYMYXIN DERIVATIVES AS ANTIMICROBIAL COMPOUNDS | VIP, PEPD, NRDC | ALDH1A1 4861/4885ALDH1A3 4859/4885ALDH3A1 4856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.