Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 15/20 | 0.70 |
| ▸ | CTSS | P25774 | 6/20 | 0.70 |
| ▸ | CTSL | P07711 | 3/20 | 0.70 |
| ▸ | CTSB | P07858 | 1/20 | 0.70 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.64 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.64 |
| ▸ | CA5A | P35218 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24115146 | 0.91 | CTSK (0.73) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL20669315 | 0.91 | CTSK (0.73) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL8245664 | 0.90 | CTSK (0.56) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL24130351 | 0.90 | CTSK (0.56) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL4032986 | 0.88 | CTSS (0.56) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL6661701 | 0.88 | CTSL (0.69) | CTSKCTSSCTSLCTSB | |
| SCHEMBL7536642 | 0.88 | CTSS (0.56) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL10790294 | 0.88 | CTSL (0.69) | CTSKCTSSCTSLCTSB | |
| SCHEMBL11361534 | 0.88 | CTSK (0.76) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL7402633 | 0.88 | CTSK (0.76) | CTSKCTSSCTSLCTSBCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996358-A | Control, prevention rheumatic diseases | HOFFMANN-LA ROCHE INC. (US) | 1991-02-26 | — | — | US | disclosed |