Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 7/20 | 0.69 |
| ▸ | CTSB | P07858 | 5/20 | 0.69 |
| ▸ | CTSS | P25774 | 4/20 | 0.69 |
| ▸ | CTSK | P43235 | 1/20 | 0.69 |
| ▸ | TACR1 | P25103 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10790294 | 1.00 | CTSL (0.69) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL10794562 | 0.92 | CTSB (0.59) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL10794564 | 0.92 | CTSB (0.59) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL11781435 | 0.91 | CTSL (0.57) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL4032986 | 0.91 | CTSS (0.56) | CTSLCTSBCTSSCTSK | |
| SCHEMBL7536642 | 0.91 | CTSS (0.56) | CTSLCTSBCTSSCTSK | |
| SCHEMBL13220863 | 0.90 | CTSL (0.72) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL7641395 | 0.90 | CTSL (0.72) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL11659096 | 0.90 | CTSL (0.57) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL24130351 | 0.89 | CTSK (0.56) | CTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200457-B1 | CYSTEINE PROTEASE INHIBITORS | NAEJA PHARMACEUTICAL INC (CA) | 2004-08-25 | — | — | EP | disclosed |
| US-6635621-B1 | Alpha amino acid amide derivatives; reducing cathepsins B, L, S and/or K activity | NAEJA PHARMACEUTICAL INC. (CA) | 2003-10-21 | — | — | US | disclosed |
| EP-1200457-A2 | CYSTEINE PROTEASE INHIBITORS | Naeja Pharmaceutical Inc. (CA) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001009169-A2 | CYSTEINE PROTEASE INHIBITORS | NAEJA PHARMACEUTICAL INC (CA) | 2001-02-08 | — | — | WO | disclosed |
| EP-0142231-B1 | PROCESS FOR PRODUCING SEQUENTIAL POLYAMINO ACID RESIN | NITTO BOSEKI CO., LTD. (JP) | 1987-11-11 | — | — | EP | disclosed |
| US-4594409-A | Polycondensation of a peptide active ester salt | NITTO BOSEKI CO., LTD. (JP) | 1986-06-10 | — | — | US | disclosed |
| EP-0142231-A1 | Process for producing sequential polyamino acid resin | NITTO BOSEKI CO., LTD. (JP) | 1985-05-22 | — | — | EP | disclosed |
| US-4173563-A | PEPTIDIZATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1979-11-06 | — | — | US | disclosed |
| US-4120853-A | Esterification of carboxylic acids by contact with a phosphonium salt | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1978-10-17 | — | — | US | disclosed |
| US-4059603-A | Esterification of carboxylic acids by contact with a phosphonium salt | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-11-22 | — | — | US | disclosed |
| US-3984417-A | Method of producing active amino acid esters | AJINOMOTO CO., INC. (JA) | 1976-10-05 | — | — | US | disclosed |
| US-3974219-A | PREPARATION PEPTIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-08-10 | — | — | US | disclosed |
| US-3933783-A | Formation of peptide bonds in the presence of isonitriles | AJINOMOTO CO., INC. (JA) | 1976-01-20 | — | — | US | disclosed |