SCHEMBL10790294

SCHEMBL10790294

CCOC(=O)CNC(=O)C(Cc1ccccc1)NC(=O)OCc1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CTSL P07711 7/20 0.69
CTSB P07858 5/20 0.69
CTSS P25774 4/20 0.69
CTSK P43235 1/20 0.69
TACR1 P25103 2/20 0.60
ALDH1A1 P00352 1/20 0.55
ALOX15 P16050 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6661701 1.00 CTSL (0.69) CTSLCTSBCTSSCTSKTACR1
SCHEMBL10794562 0.92 CTSB (0.59) CTSLCTSBCTSSCTSKTACR1
SCHEMBL10794564 0.92 CTSB (0.59) CTSLCTSBCTSSCTSKTACR1
SCHEMBL11781435 0.91 CTSL (0.57) CTSLCTSBCTSSCTSKTACR1
SCHEMBL4032986 0.91 CTSS (0.56) CTSLCTSBCTSSCTSK
SCHEMBL7536642 0.91 CTSS (0.56) CTSLCTSBCTSSCTSK
SCHEMBL13220863 0.90 CTSL (0.72) CTSLCTSBCTSSCTSKTACR1
SCHEMBL7641395 0.90 CTSL (0.72) CTSLCTSBCTSSCTSKTACR1
SCHEMBL11659096 0.90 CTSL (0.57) CTSLCTSBCTSSCTSKTACR1
SCHEMBL24130351 0.89 CTSK (0.56) CTSLCTSBCTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0142231-B1 PROCESS FOR PRODUCING SEQUENTIAL POLYAMINO ACID RESIN NITTO BOSEKI CO., LTD. (JP) 1987-11-11 EP disclosed
US-4594409-A Polycondensation of a peptide active ester salt NITTO BOSEKI CO., LTD. (JP) 1986-06-10 US disclosed
EP-0142231-A1 Process for producing sequential polyamino acid resin NITTO BOSEKI CO., LTD. (JP) 1985-05-22 EP disclosed