SCHEMBL9807101

SCHEMBL9807101

O=CCCc1cc(CCC=O)cc(CCC=O)c1

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.37
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19258592 0.84 MEN1 (0.43)
SCHEMBL2561038 0.82 DAO (0.40)
SCHEMBL7335595 0.82 DAO (0.40) TSHR
SCHEMBL27922486 0.82 MAOA (0.31)
SCHEMBL28157468 0.82 CBS (0.50) HIF1A
SCHEMBL5540678 0.82 PGK1 (0.35) ALDH1A1TSHR
SCHEMBL15609627 0.82 RAPGEF4 (0.33) ALDH1A1
SCHEMBL27790860 0.82 CA12 (0.38) HIF1AALDH1A1TSHR
SCHEMBL9671868 0.81 HIF1A (0.37) HIF1AALDH1A1
SCHEMBL585099 0.80 CES2 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0246053-B1 UNSATURATED SILYLATED VINYL ALCOHOL POLYMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-05-15 EP disclosed
EP-0165806-B1 SILYLATED VINYL ALCOHOL POLYMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-08-29 EP disclosed
US-4739021-A Unsaturated silylated vinyl alcohol polymers E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-04-19 US disclosed
EP-0165806-A2 Silylated vinyl alcohol polymers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-12-27 EP disclosed
US-4544724-A REACTING ETHENOXYSILANE AND ALDEHYDE, POLYMERIZATION, THEN HYDROLYSIS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-10-01 US disclosed