Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.34 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7751646 | 0.83 | LMNA (0.42) | LMNAPOLBALDH1A1TSHR | |
| SCHEMBL9807492 | 0.80 | POLB (0.35) | LMNAPOLBSLC6A2SLC6A4KCNH2 | |
| SCHEMBL3151346 | 0.80 | GRIN2B (0.44) | SLC6A2SLC6A4KCNH2CYP2D6SLC6A3 | |
| SCHEMBL9807522 | 0.79 | LMNA (0.40) | LMNAPOLBSLC6A2SLC6A4KCNH2 | |
| SCHEMBL9807509 | 0.79 | CA1 (0.35) | LMNAPOLBSLC6A2SLC6A4KCNH2 | |
| SCHEMBL3150553 | 0.77 | SLC6A3 (0.34) | SLC6A2SLC6A4KCNH2CYP2D6SLC6A3 | |
| SCHEMBL7750622 | 0.77 | LMNA (0.38) | LMNAPOLBSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3075356 | 0.75 | ALDH1A1 (0.41) | LMNAPOLBALDH1A1TSHR | |
| SCHEMBL9807512 | 0.75 | LMNA (0.40) | LMNAPOLBSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3361480 | 0.74 | RIPK1 (0.40) | SLC6A2SLC6A4KCNH2SLC6A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990637-A | Chemical intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-05 | — | — | US | disclosed |
| US-4927454-A | Substituted 1-benzylsulphonyl-3-heteroaryl-(thio)urea herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1990-05-22 | — | — | US | disclosed |
| US-4806147-A | Substituted 1-benzylsulphonyl-3-heteroaryl-(thio)urea herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1989-02-21 | — | — | US | disclosed |
| EP-0271780-A2 | Substituted 1-benzylsulfonyl-3-heteroaryl(thio) urea | BAYER AG (DE) | 1988-06-22 | — | — | EP | disclosed |