Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | CCR8 | P51685 | 1/20 | 0.34 |
| ▸ | CXCL8 | P10145 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | VNN1 | O95497 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9807492 | 0.87 | POLB (0.35) | LMNAPOLBKCNH2CCR8CXCL8 | |
| SCHEMBL9807509 | 0.86 | CA1 (0.35) | LMNAPOLBKCNH2CCR8CXCL8 | |
| SCHEMBL2910656 | 0.82 | HDAC3 (0.43) | KCNH2HCRTR1HCRTR2GRIN2BHDAC3 | |
| SCHEMBL8883642 | 0.80 | HDAC3 (0.42) | KCNH2HCRTR1HCRTR2GRIN2BHDAC3 | |
| SCHEMBL9807523 | 0.80 | LMNA (0.32) | LMNAPOLBKCNH2CCR8 | |
| SCHEMBL9807500 | 0.79 | LMNA (0.36) | LMNAPOLBKCNH2CCR8TSHR | |
| SCHEMBL7751646 | 0.76 | LMNA (0.42) | LMNAPOLBTSHRMAPK1ALDH1A1 | |
| SCHEMBL8060708 | 0.72 | CA2 (0.43) | LMNAPOLB | |
| SCHEMBL27805477 | 0.72 | CA2 (0.41) | LMNAPOLBTSHRMAPK1HPGD | |
| SCHEMBL8088589 | 0.70 | CXCL8 (0.54) | KCNH2CCR8CXCL8TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990637-A | Chemical intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-05 | — | — | US | disclosed |
| US-4927454-A | Substituted 1-benzylsulphonyl-3-heteroaryl-(thio)urea herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1990-05-22 | — | — | US | disclosed |
| US-4806147-A | Substituted 1-benzylsulphonyl-3-heteroaryl-(thio)urea herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1989-02-21 | — | — | US | disclosed |
| EP-0271780-A2 | Substituted 1-benzylsulfonyl-3-heteroaryl(thio) urea | BAYER AG (DE) | 1988-06-22 | — | — | EP | disclosed |