Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9807963 | 0.82 | ALDH1A1 (0.41) | KDM4ENPC1ALDH1A1HSD17B10HPGD | |
| SCHEMBL9807923 | 0.81 | MAPT (0.41) | KDM4ENPC1ALDH1A1HSD17B10HPGD | |
| SCHEMBL11416817 | 0.78 | DHODH (0.50) | KDM4ENPC1ALDH1A1HSD17B10HPGD | |
| SCHEMBL11262382 | 0.75 | DHODH (0.55) | NPC1MAPTKMT2AADORA1PARP1 | |
| SCHEMBL9807926 | 0.73 | GSK3B (0.41) | KDM4ENPC1ALDH1A1HPGDMAPT | |
| SCHEMBL11246290 | 0.73 | CYP11B2 (0.43) | KDM4ENPC1ALDH1A1HSD17B10HPGD | |
| SCHEMBL11250627 | 0.72 | DHODH (0.45) | ADORA1PARP1 | |
| SCHEMBL21306416 | 0.71 | PDE10A (0.48) | KDM4ENPC1ALDH1A1HSD17B10HPGD | |
| SCHEMBL12145408 | 0.70 | ALDH1A1 (0.43) | KDM4ENPC1ALDH1A1HSD17B10HPGD | |
| SCHEMBL9807880 | 0.68 | RAB9A (0.41) | KDM4ENPC1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994448-A | Analgesics, anesthetics, muscle relaxants | EGIS GYOGYSZERGYAR (HU) | 1991-02-19 | — | — | US | disclosed |