Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.48 |
| ▸ | TUBB | P07437 | 2/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.48 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.48 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.48 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.48 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.48 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27703189 | 0.84 | ALDH1A1 (0.50) | ALDH1A1TDP1TUBB4ATUBBTUBA3C | |
| SCHEMBL9808919 | 0.80 | ALDH1A1 (0.54) | ALDH1A1TDP1TUBB4ATUBBTUBA3C | |
| SCHEMBL9808915 | 0.78 | PDGFRB (0.53) | ALDH1A1TDP1TUBB4ATUBBTUBA3C | |
| SCHEMBL14618103 | 0.77 | CA2 (0.45) | ALDH1A1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1119379 | 0.76 | LMNA (0.59) | ALDH1A1TDP1TUBB4ATUBBTUBA3C | |
| SCHEMBL29485957 | 0.76 | LMNA (0.59) | ALDH1A1TDP1TUBB4ATUBBTUBA3C | |
| SCHEMBL10505223 | 0.76 | VCAM1 (0.51) | TDP1TSHR | |
| SCHEMBL22137287 | 0.75 | SIRT6 (0.54) | ALDH1A1TDP1TUBB4ATUBBTUBA3C | |
| SCHEMBL31480878 | 0.74 | ALDH1A1 (0.50) | ALDH1A1TDP1TUBB4ATUBBTUBA3C | |
| SCHEMBL20328412 | 0.74 | TDP1 (0.66) | ALDH1A1TDP1TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2760838-B1 | DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARM SPA (IT) | 2017-05-10 | — | — | EP | disclosed |