Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9809118 | 0.88 | POLB (0.42) | POLBHSD11B1ALDH1A1ALOX15BCHE | |
| SCHEMBL9809067 | 0.81 | CYP19A1 (0.42) | POLBHSD11B1ALDH1A1ALOX15BCHE | |
| SCHEMBL9809069 | 0.80 | ALOX15 (0.58) | POLBALDH1A1ALOX15BCHEPTGS2 | |
| SCHEMBL9809074 | 0.78 | KMT2A (0.47) | ALDH1A1LMNAMEN1KMT2ANPSR1 | |
| SCHEMBL6260403 | 0.76 | BCHE (0.63) | POLBHSD11B1ALDH1A1ALOX15BCHE | |
| SCHEMBL15550275 | 0.74 | ABCB1 (0.52) | ALDH1A1ALOX15ABCB1TSHR | |
| SCHEMBL15537298 | 0.74 | ALDH1A1 (0.69) | POLBHSD11B1ALDH1A1ALOX15BCHE | |
| SCHEMBL9809094 | 0.73 | FPR2 (0.45) | POLBALDH1A1ALOX15BCHEPTGS2 | |
| SCHEMBL23403514 | 0.71 | ALDH1A1 (0.44) | ALDH1A1LMNAMEN1KMT2AABCB1 | |
| SCHEMBL9809114 | 0.71 | CYP19A1 (0.43) | POLBALDH1A1ALOX15BCHEPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5063245-A | Hormone inhibitors | NOVA PHARMACEUTICAL CORPORATION (US) | 1991-11-05 | — | — | US | disclosed |