Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.41 |
| ▸ | HTR3B | O95264 | 3/20 | 0.41 |
| ▸ | HTR3A | P46098 | 3/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | XPO1 | O14980 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9809099 | 0.89 | HTR3E (0.39) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL9809111 | 0.85 | CYP19A1 (0.37) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL17035402 | 0.72 | NAPRT (0.50) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL9809065 | 0.70 | ALOX15 (0.62) | ALDH1A1MAPTKMT2AMEN1TSHR | |
| SCHEMBL9809089 | 0.70 | GSK3A (0.41) | ALDH1A1MAPTKMT2AMEN1BCHE | |
| SCHEMBL17035278 | 0.66 | BCHE (0.55) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL9809075 | 0.65 | BCHE (0.47) | ALDH1A1MAPTKMT2ATSHRCYP1A2 | |
| SCHEMBL24190264 | 0.64 | FPR2 (0.43) | — | |
| SCHEMBL9809062 | 0.63 | CYP19A1 (0.38) | ALDH1A1CYP19A1MAPTKMT2AMEN1 | |
| SCHEMBL1455672 | 0.62 | HTR3E (0.50) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5063245-A | Hormone inhibitors | NOVA PHARMACEUTICAL CORPORATION (US) | 1991-11-05 | — | — | US | disclosed |