Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9809101 | 0.89 | KMT2A (0.40) | KMT2AGAAL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL9809085 | 0.85 | L3MBTL1 (0.38) | KMT2AGAAL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL9809118 | 0.79 | POLB (0.42) | KMT2AGAAALDH1A1MEN1 | |
| SCHEMBL9809071 | 0.71 | KDM4E (0.41) | KMT2AGAAL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL4326087 | 0.68 | ELANE (0.40) | KMT2AGAAALDH1A1MEN1HTT | |
| SCHEMBL9809121 | 0.68 | POLB (0.40) | KMT2AGAAALDH1A1MEN1 | |
| SCHEMBL9809067 | 0.65 | CYP19A1 (0.42) | KMT2AGAAL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL9809061 | 0.64 | MGLL (0.37) | KMT2AL3MBTL1ALDH1A1HTTMAPT | |
| SCHEMBL11455608 | 0.61 | BCL2A1 (0.60) | KMT2AALDH1A1MEN1MAPTBCL2A1 | |
| SCHEMBL3529330 | 0.60 | ALDH1A1 (0.38) | KMT2AGAAL3MBTL1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5063245-A | Hormone inhibitors | NOVA PHARMACEUTICAL CORPORATION (US) | 1991-11-05 | — | — | US | disclosed |