Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MAT2A | P31153 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9809085 | 0.86 | L3MBTL1 (0.38) | ALDH1A1MAPTL3MBTL1GAAKMT2A | |
| SCHEMBL9809067 | 0.86 | CYP19A1 (0.42) | KDM4ENPSR1BCHEALDH1A1MAPT | |
| SCHEMBL9809061 | 0.77 | MGLL (0.37) | KDM4EMGLLALDH1A1MAPTL3MBTL1 | |
| SCHEMBL9809114 | 0.76 | CYP19A1 (0.43) | KDM4ENPSR1BCHEALDH1A1MAPT | |
| SCHEMBL9809076 | 0.72 | ALDH1A1 (0.44) | KDM4ENPSR1ALDH1A1MAPTTSHR | |
| SCHEMBL9809093 | 0.71 | KMT2A (0.41) | ALDH1A1MAPTL3MBTL1GAAKMT2A | |
| SCHEMBL9809118 | 0.70 | POLB (0.42) | NPSR1BCHEALDH1A1TSHRGAA | |
| SCHEMBL9809064 | 0.70 | NOX4 (0.45) | BCHEALDH1A1MAPTNOX4GAA | |
| SCHEMBL9809062 | 0.69 | CYP19A1 (0.38) | BCHEALDH1A1MAPTL3MBTL1TSHR | |
| SCHEMBL3882745 | 0.68 | CYP19A1 (0.56) | KDM4EBCHEALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5063245-A | Hormone inhibitors | NOVA PHARMACEUTICAL CORPORATION (US) | 1991-11-05 | — | — | US | disclosed |