Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 18/20 | 0.47 |
| ▸ | HRH1 | P35367 | 18/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9809305 | 0.88 | USP2 (0.59) | HRH2HRH1DRD2USP2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9809253 | 0.86 | ALDH1A1 (0.58) | HRH2HRH1DRD2USP2ALDH1A1 | |
| SCHEMBL9809411 | 0.79 | HRH2 (0.49) | HRH2HRH1DRD2 | |
| Hydrochloric Acid SCHEMBL9809260 | 0.79 | HRH2 (0.67) | HRH2HRH1DRD2 | |
| SCHEMBL9809292 | 0.77 | HRH2 (0.64) | HRH2HRH1DRD2 | |
| SCHEMBL9809306 | 0.77 | DRD2 (0.53) | HRH1DRD2 | |
| SCHEMBL10804830 | 0.75 | HRH2 (0.45) | HRH2HRH1ALDH1A1 | |
| SCHEMBL9809265 | 0.72 | HRH1 (0.63) | HRH2HRH1DRD2USP2ALDH1A1 | |
| SCHEMBL9809355 | 0.70 | USP2 (0.59) | HRH2HRH1DRD2USP2ALDH1A1 | |
| SCHEMBL14367448 | 0.70 | DRD2 (0.54) | HRH2HRH1DRD2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0211928-B1 | PIPERAZINECARBOXAMIDES HAVING A PHENOXYALKYL OR THIOPHENOXYALKYL SIDE CHAIN | AB LEO (SE) | 1991-05-02 | — | — | EP | disclosed |