SCHEMBL981060

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL578915	0.83	IMPDH2 (0.59)	IMPDH2IMPDH1CCNT1CDK9HASPIN
	SCHEMBL27708665	0.80	IMPDH2 (1.00)	IMPDH2IMPDH1MAPTALDH1A1HPGD
	SCHEMBL4776295	0.80	IMPDH2 (0.48)	IMPDH2IMPDH1GLACCNT1CDK9
	SCHEMBL8291070	0.78	ALDH1A1 (0.47)	MAPTALDH1A1ESR2HSD17B10HPGD
	SCHEMBL11924851	0.76	IMPDH2 (0.52)	IMPDH2IMPDH1CCNT1CDK9HASPIN
	SCHEMBL12109387	0.76	IMPDH2 (0.56)	IMPDH2IMPDH1CCNT1CDK9HASPIN
	SCHEMBL12996747	0.76	IMPDH2 (0.56)	IMPDH2IMPDH1CCNT1CDK9HASPIN
	SCHEMBL27786649	0.75	IMPDH2 (0.59)	IMPDH2IMPDH1CCNT1CDK9HASPIN
	SCHEMBL6184647	0.74	IMPDH2 (0.51)	IMPDH2ALDH1A1HPGDPRKAB2PRKAG1
	SCHEMBL24612211	0.74	IMPDH2 (0.50)	IMPDH2IMPDH1CCNT1CDK9HASPIN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.