SCHEMBL9810885

SCHEMBL9810885

Oc1ccccc1-c1c(O)cccc1[SiH3]

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.48
MAPT P10636 7/20 0.46
ALDH1A1 P00352 6/20 0.46
HPGD P15428 6/20 0.46
HSD17B10 Q99714 6/20 0.46
ALOX15 P16050 5/20 0.46
TDP1 Q9NUW8 5/20 0.46
SMN1; SMN2 Q16637 4/20 0.46
MAPK1 P28482 3/20 0.46
LMNA P02545 3/20 0.46
TSHR P16473 1/20 0.46
MAOB P27338 1/20 0.46
HTT P42858 1/20 0.46
BCL2L1 Q07817 1/20 0.46
RECQL P46063 6/20 0.43
KDM4E B2RXH2 5/20 0.43
KMT2A Q03164 4/20 0.43
IDO1 P14902 4/20 0.43
MEN1 O00255 3/20 0.43
CYP3A4 P08684 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29837181 0.85 MAOA (0.56) MAOAMAPTALDH1A1HPGDHSD17B10
SCHEMBL2729251 0.85 MAOA (0.56) MAOAMAPTALDH1A1HPGDHSD17B10
SCHEMBL30710585 0.82 ALOX15 (0.47) MAOAMAPTALDH1A1HPGDHSD17B10
SCHEMBL29469517 0.80 MAOA (0.52) MAOAMAPTALDH1A1HPGDHSD17B10
SCHEMBL29455667 0.80 MAOA (0.52) MAOAMAPTALDH1A1HPGDHSD17B10
SCHEMBL31623901 0.78 MAOA (0.50) MAOAMAPTALDH1A1HPGDHSD17B10
SCHEMBL31534010 0.78 MAOA (0.50) MAOAMAPTALDH1A1HPGDHSD17B10
SCHEMBL4390436 0.77 ALDH1A1 (0.52) MAOAMAPTALDH1A1HPGDHSD17B10
SCHEMBL7911398 0.76 MAOA (0.48) MAOAMAPTALDH1A1HPGDHSD17B10
SCHEMBL7583763 0.74 TRPA1 (0.50) MAOAMAPTALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0398049-A2 Polymeric reaction products of biphenols and organosilicon materials and method for making GENERAL ELECTRIC COMPANY (US) 1990-11-22 EP claimed
US-5041514-A Polymeric reaction products of biphenols and organosilicon materials and method for making GENERAL ELECTRIC COMPANY (US) 1991-08-20 US disclosed
EP-0398049-A2 Polymeric reaction products of biphenols and organosilicon materials and method for making GENERAL ELECTRIC COMPANY (US) 1990-11-22 EP disclosed